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- W2007305576 abstract "Introduction: Potential minimally invasive lung cancer therapies such as brachytherapy will require intraoperative imaging for both instrument tracking and tumour volume measurements for radiation dose planning. Ultrasound (US) is the modality of choice because it is inexpensive, real-time, portable, and non-invasive to the patient. Objectives: We have developed a lung tumour model, using excised porcine lung and agar tumours, to provide a means of verifying volume measurements of 3D US images in ex vivo lung tissue. Methods: Spherical tumours were made from agar with diameters of 9.5mm to 25.4mm. The tumours were inserted through incisions on the underside of the excised porcine lung. The lung was placed in a box with ports and the thoracoscopic US probe was inserted through a port for imaging. One observer measured the tumour image volumes five times, once every two days, using a radial segmentation algorithm with an interslice thickness of three degrees. Results: Both the coefficient of variation (COV) and percent difference decreased as the tumour size increased. The average COV and percent difference were 11.2% and 12.9%, respectively. Conclusions: 3D Thoracoscopic US can be used accurately and reproducibly to measure tumour volumes in vitro." @default.
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- W2007305576 date "2005-06-23" @default.
- W2007305576 modified "2023-09-26" @default.
- W2007305576 title "Sci-PM Thurs - 08: Development of a lung tumour model for validating three-dimensional thoracoscopic ultrasound imaging" @default.
- W2007305576 doi "https://doi.org/10.1118/1.2030978" @default.
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