Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007307316> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2007307316 endingPage "385" @default.
- W2007307316 startingPage "378" @default.
- W2007307316 abstract "Depression of myocardial contractility after ethanol ingestion in man has previously been shown only in patients with heart disease. In the present study, normal subjects, aged 23-30 years, ingested six ounces of 43% alcohol over a two hour period (Group I, 6 subjects) or a one hour period (Group II, 5 subjects). Systolic time intervals were measured every 15 min from simultaneous ECG, phonocardiogram and carotid pulse tracings. Heart rate, total electromechanical systole and left ventricular ejection time (LVET) were not changed at any time from pre-alcohol values and, except for a small (5 mm Hg) and transient change in diastolic pressure in Group II, aortic pressures also were unchanged. However, in Group I, after 60 min, at a blood ethanol of 74 ± 3 mg%, left ventricular depression was manifested by increased pre-ejection period (PEP) from 90 ± 2 to 96 ± 3.1 msec, isovolumic time (IVT) from 44 ± 3.5 to 52 ± 4 ( P < .01), and PEP/LVET ratio from 0.299 ± 0.009 to 0.323 ± 0.01 ( P < .05). Further depression occurred at two hours with blood ethanol at 111 ± 6 mg%. Doubling ingestion rate (Group II) produced reduction of left ventricular performance at 30 min at a blood level of 50 ± 3 mg%. Feeding of isocaloric sucrose in 5 subjects (Group III) as a control produced a decrease in PEP, IVT, and PEP/LVET. Thus, alcohol in nonintoxicating doses elicits a depression of cardiovascular function in normal unhabituated subjects." @default.
- W2007307316 created "2016-06-24" @default.
- W2007307316 creator A5029439529 @default.
- W2007307316 creator A5060302173 @default.
- W2007307316 creator A5091287727 @default.
- W2007307316 date "1973-08-01" @default.
- W2007307316 modified "2023-10-12" @default.
- W2007307316 title "Depression of Myocardial Contractility with Low Doses of Ethanol in Normal Man" @default.
- W2007307316 cites W1989918610 @default.
- W2007307316 cites W1991759728 @default.
- W2007307316 cites W1997320242 @default.
- W2007307316 cites W2002154885 @default.
- W2007307316 cites W2018432292 @default.
- W2007307316 cites W2027086308 @default.
- W2007307316 cites W2027820790 @default.
- W2007307316 cites W2031993898 @default.
- W2007307316 cites W2032605459 @default.
- W2007307316 cites W2040746652 @default.
- W2007307316 cites W2048664143 @default.
- W2007307316 cites W2059349647 @default.
- W2007307316 cites W2088641152 @default.
- W2007307316 cites W2329745284 @default.
- W2007307316 cites W4298136025 @default.
- W2007307316 doi "https://doi.org/10.1161/01.cir.48.2.378" @default.
- W2007307316 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4726217" @default.
- W2007307316 hasPublicationYear "1973" @default.
- W2007307316 type Work @default.
- W2007307316 sameAs 2007307316 @default.
- W2007307316 citedByCount "116" @default.
- W2007307316 countsByYear W20073073162012 @default.
- W2007307316 crossrefType "journal-article" @default.
- W2007307316 hasAuthorship W2007307316A5029439529 @default.
- W2007307316 hasAuthorship W2007307316A5060302173 @default.
- W2007307316 hasAuthorship W2007307316A5091287727 @default.
- W2007307316 hasBestOaLocation W20073073161 @default.
- W2007307316 hasConcept C126322002 @default.
- W2007307316 hasConcept C139719470 @default.
- W2007307316 hasConcept C159693508 @default.
- W2007307316 hasConcept C162324750 @default.
- W2007307316 hasConcept C164705383 @default.
- W2007307316 hasConcept C169554166 @default.
- W2007307316 hasConcept C2776867660 @default.
- W2007307316 hasConcept C2777953023 @default.
- W2007307316 hasConcept C39078644 @default.
- W2007307316 hasConcept C39133596 @default.
- W2007307316 hasConcept C42219234 @default.
- W2007307316 hasConcept C57900726 @default.
- W2007307316 hasConcept C71924100 @default.
- W2007307316 hasConcept C84393581 @default.
- W2007307316 hasConceptScore W2007307316C126322002 @default.
- W2007307316 hasConceptScore W2007307316C139719470 @default.
- W2007307316 hasConceptScore W2007307316C159693508 @default.
- W2007307316 hasConceptScore W2007307316C162324750 @default.
- W2007307316 hasConceptScore W2007307316C164705383 @default.
- W2007307316 hasConceptScore W2007307316C169554166 @default.
- W2007307316 hasConceptScore W2007307316C2776867660 @default.
- W2007307316 hasConceptScore W2007307316C2777953023 @default.
- W2007307316 hasConceptScore W2007307316C39078644 @default.
- W2007307316 hasConceptScore W2007307316C39133596 @default.
- W2007307316 hasConceptScore W2007307316C42219234 @default.
- W2007307316 hasConceptScore W2007307316C57900726 @default.
- W2007307316 hasConceptScore W2007307316C71924100 @default.
- W2007307316 hasConceptScore W2007307316C84393581 @default.
- W2007307316 hasIssue "2" @default.
- W2007307316 hasLocation W20073073161 @default.
- W2007307316 hasLocation W20073073162 @default.
- W2007307316 hasOpenAccess W2007307316 @default.
- W2007307316 hasPrimaryLocation W20073073161 @default.
- W2007307316 hasRelatedWork W152778644 @default.
- W2007307316 hasRelatedWork W2008825783 @default.
- W2007307316 hasRelatedWork W2016818225 @default.
- W2007307316 hasRelatedWork W2052723448 @default.
- W2007307316 hasRelatedWork W2088651346 @default.
- W2007307316 hasRelatedWork W2129645691 @default.
- W2007307316 hasRelatedWork W2140715215 @default.
- W2007307316 hasRelatedWork W2312780947 @default.
- W2007307316 hasRelatedWork W2412645385 @default.
- W2007307316 hasRelatedWork W2953090977 @default.
- W2007307316 hasVolume "48" @default.
- W2007307316 isParatext "false" @default.
- W2007307316 isRetracted "false" @default.
- W2007307316 magId "2007307316" @default.
- W2007307316 workType "article" @default.