FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007309660> ?p ?o ?g. }

• W2007309660 endingPage "297" @default.
• W2007309660 startingPage "288" @default.
• W2007309660 abstract "The in‐vitro activity of enrofloxacin against 117 strains of bacteria isolated from bustards was determined. Minimum inhibitory concentrations for 72% of the Proteus spp., E. coli , Salmonella spp. and Klebsiella spp. ( n = 61) and for 48% of the Streptococci spp. and Staphylococci spp. ( n = 31) were 0.5 μ g/mL. The minimum inhibitory concentration (MIC) of 76% of Pseudomonas spp. ( n = 25) was 2 μg/mL. Fourteen strains were resistant to concentrations 128 μg/mL. The elimination half‐lives ( t ½ elim β) (mean± SEM) of 10 mg/kg enrofloxacin in eight houbara bustards ( Chlamydotis undulata ) were 6.80± 0.79, 6.39± 1.49 and 5.63± 0.54 h after oral (p.o.), intramuscular (i.m.) and intravenous (i.v.) administration, respectively. Enrofloxacin was rapidly absorbed from the bustard gastro‐intestinal tract and maximum plasma concentrations of 1.84± 0.16 μg/mL were achieved after 0.66± 0.05 h. Maximum plasma concentration after i.m. administration of 10 mg/kg was 2.75± 0.11 μg/mL at 1.72± 0.19 h. Maximum plasma concentration after i.m. administration of 15 mg/kg in two birds was 4.86 μg/mL. Bioavailability was 97.3± 13.7% and 62.7± 11.1% after i.m. and oral administration, respectively. Plasma concentrations of enrofloxacin 0.5 μg/mL were maintained for at least 12 h for all routes at 10 mg/kg and for 24 h after i.m. administration at 15 mg/kg. Plasma enrofloxacin concentrations were monitored during the first 3 days of treatment in five houbara bustards and kori bustards ( Ardeotis kori ) with bacterial infections receiving a single daily i.m. injection of 10 mg/kg for 3 days. The mean plasma enrofloxacin concentrations in the clinical cases at 27 and 51 h (3.69 and 3.86 μg/mL) and at 48 h (0.70 μg/mL) were significantly higher compared with the 3 h and 24 h time intervals from clinically normal birds. The maximum plasma concentration ( C max )/MIC ratio was ranked i.v. (10/mg/kg) > i.m. (15 mg/kg) > i.m. (10 mg/kg) > oral (10 mg/kg), but it was only higher than 8:1 for i.v and i.m. administrations of enrofloxacin at 10 mg/kg and 15 mg/kg, respectively, against a low MIC (0.5 μg/mL). A dosage regimen of 10 mg/kg repeated every 12 h, or 15 mg/kg repeated every 24 h, would be expected to give blood concentrations above 0.5 μg/mL and hence provide therapeutic response in the bustard against a wide range of bacterial infections." @default.
• W2007309660 created "2016-06-24" @default.
• W2007309660 creator A5016033818 @default.
• W2007309660 creator A5043182058 @default.
• W2007309660 creator A5043462168 @default.
• W2007309660 creator A5047300535 @default.
• W2007309660 creator A5060717346 @default.
• W2007309660 creator A5076700082 @default.
• W2007309660 date "1998-08-01" @default.
• W2007309660 modified "2023-09-25" @default.
• W2007309660 title "Pharmacokinetics of enrofloxacin after intravenous, intramuscular and oral administration in houbara bustard (<i>Chlamydotis undulata macqueenii</i>)" @default.
• W2007309660 cites W1968365072 @default.
• W2007309660 cites W1980982717 @default.
• W2007309660 cites W1987971680 @default.
• W2007309660 cites W2001663765 @default.
• W2007309660 cites W2011526453 @default.
• W2007309660 cites W2017169078 @default.
• W2007309660 cites W2023304254 @default.
• W2007309660 cites W2027488940 @default.
• W2007309660 cites W2029935652 @default.
• W2007309660 cites W2036487127 @default.
• W2007309660 cites W2058681803 @default.
• W2007309660 cites W2068301725 @default.
• W2007309660 cites W2073859633 @default.
• W2007309660 cites W2089163466 @default.
• W2007309660 cites W2111260540 @default.
• W2007309660 cites W2127166970 @default.
• W2007309660 cites W2134126932 @default.
• W2007309660 cites W2144430247 @default.
• W2007309660 cites W2147264575 @default.
• W2007309660 cites W2154497288 @default.
• W2007309660 cites W2165411023 @default.
• W2007309660 cites W2171817977 @default.
• W2007309660 doi "https://doi.org/10.1046/j.1365-2885.1998.00143.x" @default.
• W2007309660 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9731951" @default.
• W2007309660 hasPublicationYear "1998" @default.
• W2007309660 type Work @default.
• W2007309660 sameAs 2007309660 @default.
• W2007309660 citedByCount "40" @default.
• W2007309660 countsByYear W20073096602012 @default.
• W2007309660 countsByYear W20073096602013 @default.
• W2007309660 countsByYear W20073096602014 @default.
• W2007309660 countsByYear W20073096602015 @default.
• W2007309660 countsByYear W20073096602016 @default.
• W2007309660 countsByYear W20073096602017 @default.
• W2007309660 countsByYear W20073096602019 @default.
• W2007309660 countsByYear W20073096602021 @default.
• W2007309660 countsByYear W20073096602022 @default.
• W2007309660 countsByYear W20073096602023 @default.
• W2007309660 crossrefType "journal-article" @default.
• W2007309660 hasAuthorship W2007309660A5016033818 @default.
• W2007309660 hasAuthorship W2007309660A5043182058 @default.
• W2007309660 hasAuthorship W2007309660A5043462168 @default.
• W2007309660 hasAuthorship W2007309660A5047300535 @default.
• W2007309660 hasAuthorship W2007309660A5060717346 @default.
• W2007309660 hasAuthorship W2007309660A5076700082 @default.
• W2007309660 hasConcept C112705442 @default.
• W2007309660 hasConcept C140793950 @default.
• W2007309660 hasConcept C176947019 @default.
• W2007309660 hasConcept C181389837 @default.
• W2007309660 hasConcept C185592680 @default.
• W2007309660 hasConcept C2777056448 @default.
• W2007309660 hasConcept C2778512257 @default.
• W2007309660 hasConcept C2779906673 @default.
• W2007309660 hasConcept C42972112 @default.
• W2007309660 hasConcept C501593827 @default.
• W2007309660 hasConcept C71924100 @default.
• W2007309660 hasConcept C86803240 @default.
• W2007309660 hasConcept C89423630 @default.
• W2007309660 hasConcept C98274493 @default.
• W2007309660 hasConceptScore W2007309660C112705442 @default.
• W2007309660 hasConceptScore W2007309660C140793950 @default.
• W2007309660 hasConceptScore W2007309660C176947019 @default.
• W2007309660 hasConceptScore W2007309660C181389837 @default.
• W2007309660 hasConceptScore W2007309660C185592680 @default.
• W2007309660 hasConceptScore W2007309660C2777056448 @default.
• W2007309660 hasConceptScore W2007309660C2778512257 @default.
• W2007309660 hasConceptScore W2007309660C2779906673 @default.
• W2007309660 hasConceptScore W2007309660C42972112 @default.
• W2007309660 hasConceptScore W2007309660C501593827 @default.
• W2007309660 hasConceptScore W2007309660C71924100 @default.
• W2007309660 hasConceptScore W2007309660C86803240 @default.
• W2007309660 hasConceptScore W2007309660C89423630 @default.
• W2007309660 hasConceptScore W2007309660C98274493 @default.
• W2007309660 hasIssue "4" @default.
• W2007309660 hasLocation W20073096601 @default.
• W2007309660 hasLocation W20073096602 @default.
• W2007309660 hasOpenAccess W2007309660 @default.
• W2007309660 hasPrimaryLocation W20073096601 @default.
• W2007309660 hasRelatedWork W1495653742 @default.
• W2007309660 hasRelatedWork W2001333918 @default.
• W2007309660 hasRelatedWork W2022148560 @default.
• W2007309660 hasRelatedWork W2075612064 @default.
• W2007309660 hasRelatedWork W2084150350 @default.
• W2007309660 hasRelatedWork W2153118441 @default.
• W2007309660 hasRelatedWork W2314489661 @default.
• W2007309660 hasRelatedWork W2361066783 @default.
• W2007309660 hasRelatedWork W2414263157 @default.

• next