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- W2007314980 abstract "Histidyl-proline diketopiperazine or cyclo(His-Pro) [CHP] is a peptide which occurs in a variety of tissues and body fluids. The administration of exogenous peptide has been shown to elicit a variety of biologic activities, including a decrease in dietary fat preference. Our recent observation of the presence of uncharacterized CHP-like immunoreactivity (CHP-LI) in milk has led us to develop a method for the isolation, characterization and measurement of CHP in milk and yogurt. We measured CHP in a herd of 27 cows randomly selected from LSU Department of Dairy Science Research Herd in Baton Rouge; the results of this study show a mean peptide concentration in milk of 0.92 ± 0.37 ng/ml, with a median concentration of 0.84 and a range of 0.35 to 1.90 ng/ml. The level of CHP in milk did not change significantly with the stage of lactation; however, it decreased with an increase in level of milk production. The results of this study show the presence of CHP in milk and other dairy products, the food group that constitutes a major part of our diet. Further studies are needed to understand the factors regulating levels of CHP in milk and other dairy products." @default.
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- W2007314980 date "1995-11-01" @default.
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- W2007314980 title "Hormones in foods: Abundance of authentic cyclo(His-Pro)-like immunoreactivity in milk and yogurt" @default.
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- W2007314980 doi "https://doi.org/10.1016/0271-5317(95)02033-1" @default.
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