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- W2007325644 abstract "Even the most trivial combat wound is regularly contaminated with soil. Unless this foreign body is adequately cleansed from the wound the risk of subsequent infection is great. The causal factors for this deleterious effect of soil have, until now, been unknown. Results of this study have led to the identification of the factors in soil that potentiate the development of infection. When an injury contained as few as 100 bacteria, the addition of 5 mg of soil led to infection. When this soil sample was fractionated, it was found that the infection-potentiating factors (IPFs) resided predominantly in the clay or organic soil fractions or both. The type of cation adsorbed by the surface of the IPF did not influence its toxic effects on tissues. Silicate clay fractions contain several colloidal clay minerals: montmorillonite, illite, and kaolinite. Montmorillonite clay enhanced the development of infection more than did illite or kaolinite. The IPFs in organic and clay fractions of soil can be characterized by their large surface area and high cation exchange capacity. This physical property of the IPFs ensures an active chemical exchange between the wound and the IPFs which may account for their deleterious effects. Isolation and identification of the factors in soil that potentiate infection will enable us to develop technics for the efficient removal of these agents based on modern pedologic methods." @default.
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- W2007325644 date "1974-07-01" @default.
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- W2007325644 title "Identification of the wound infection-potentiating factors in soil" @default.
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- W2007325644 doi "https://doi.org/10.1016/0002-9610(74)90226-8" @default.
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