Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007334806> ?p ?o ?g. }
- W2007334806 endingPage "9" @default.
- W2007334806 startingPage "1" @default.
- W2007334806 abstract "Development of induced pluripotent stem cells (iPSCs) using forced expression of specific sets of transcription factors has changed the field of stem cell research extensively. Two important limitations for research application of embryonic stem cells (ESCs), namely, ethical and immunological issues, can be circumvented using iPSCs. Since the development of first iPSCs, tremendous effort has been directed to the development of methods to increase the efficiency of the process and to reduce the extent of genomic modifications associated with the reprogramming procedure. The established lineage-specific differentiation protocols developed for ESCs are being applied to iPSCs, as they have great potential in regenerative medicine for cell therapy, disease modeling either for drug development or for fundamental science, and, last but not least, toxicity testing. This paper reviews efforts aimed at practical development of iPSC differentiation to neural/cardiac lineages and further the use of these iPSCs-derived cells for drug development and toxicity testing." @default.
- W2007334806 created "2016-06-24" @default.
- W2007334806 creator A5026227604 @default.
- W2007334806 creator A5053589110 @default.
- W2007334806 creator A5090623663 @default.
- W2007334806 date "2012-01-01" @default.
- W2007334806 modified "2023-09-26" @default.
- W2007334806 title "Drug Discovery Models and Toxicity Testing Using Embryonic and Induced Pluripotent Stem-Cell-Derived Cardiac and Neuronal Cells" @default.
- W2007334806 cites W1895993106 @default.
- W2007334806 cites W1967379086 @default.
- W2007334806 cites W1970305312 @default.
- W2007334806 cites W1972434468 @default.
- W2007334806 cites W1976874039 @default.
- W2007334806 cites W1978173381 @default.
- W2007334806 cites W1979904726 @default.
- W2007334806 cites W1985010554 @default.
- W2007334806 cites W1985300858 @default.
- W2007334806 cites W1985494276 @default.
- W2007334806 cites W1985964771 @default.
- W2007334806 cites W1989836279 @default.
- W2007334806 cites W1991037959 @default.
- W2007334806 cites W1992525863 @default.
- W2007334806 cites W1993064034 @default.
- W2007334806 cites W1995864831 @default.
- W2007334806 cites W2003126320 @default.
- W2007334806 cites W2006312138 @default.
- W2007334806 cites W2008905720 @default.
- W2007334806 cites W2011844821 @default.
- W2007334806 cites W2018040454 @default.
- W2007334806 cites W2022669480 @default.
- W2007334806 cites W2024119772 @default.
- W2007334806 cites W2024442620 @default.
- W2007334806 cites W2031383358 @default.
- W2007334806 cites W2033448771 @default.
- W2007334806 cites W2034089536 @default.
- W2007334806 cites W2035181962 @default.
- W2007334806 cites W2035792120 @default.
- W2007334806 cites W2041171500 @default.
- W2007334806 cites W2045859114 @default.
- W2007334806 cites W2045899482 @default.
- W2007334806 cites W2046013132 @default.
- W2007334806 cites W2056413676 @default.
- W2007334806 cites W2058196652 @default.
- W2007334806 cites W2060801754 @default.
- W2007334806 cites W2061778565 @default.
- W2007334806 cites W2061792807 @default.
- W2007334806 cites W2065901519 @default.
- W2007334806 cites W2066058435 @default.
- W2007334806 cites W2066748034 @default.
- W2007334806 cites W2068278508 @default.
- W2007334806 cites W2071458966 @default.
- W2007334806 cites W2073117828 @default.
- W2007334806 cites W2074070702 @default.
- W2007334806 cites W2074404174 @default.
- W2007334806 cites W2077477761 @default.
- W2007334806 cites W2083074520 @default.
- W2007334806 cites W2086486740 @default.
- W2007334806 cites W2086943348 @default.
- W2007334806 cites W2088606003 @default.
- W2007334806 cites W2092647929 @default.
- W2007334806 cites W2093441343 @default.
- W2007334806 cites W2094307313 @default.
- W2007334806 cites W2098597036 @default.
- W2007334806 cites W2100417606 @default.
- W2007334806 cites W2103540918 @default.
- W2007334806 cites W2104996733 @default.
- W2007334806 cites W2106379660 @default.
- W2007334806 cites W2106485710 @default.
- W2007334806 cites W2107660300 @default.
- W2007334806 cites W2111738380 @default.
- W2007334806 cites W2115089758 @default.
- W2007334806 cites W2121262376 @default.
- W2007334806 cites W2125619687 @default.
- W2007334806 cites W2125987139 @default.
- W2007334806 cites W2126774748 @default.
- W2007334806 cites W2127260798 @default.
- W2007334806 cites W2128362126 @default.
- W2007334806 cites W2134411214 @default.
- W2007334806 cites W2138977668 @default.
- W2007334806 cites W2142046859 @default.
- W2007334806 cites W2144376639 @default.
- W2007334806 cites W2145137957 @default.
- W2007334806 cites W2145492799 @default.
- W2007334806 cites W2152483372 @default.
- W2007334806 cites W2158979552 @default.
- W2007334806 cites W2158992759 @default.
- W2007334806 cites W2159071874 @default.
- W2007334806 cites W2163107380 @default.
- W2007334806 cites W3105032491 @default.
- W2007334806 cites W4246383450 @default.
- W2007334806 doi "https://doi.org/10.1155/2012/379569" @default.
- W2007334806 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3357635" @default.
- W2007334806 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22654918" @default.
- W2007334806 hasPublicationYear "2012" @default.
- W2007334806 type Work @default.
- W2007334806 sameAs 2007334806 @default.
- W2007334806 citedByCount "39" @default.
- W2007334806 countsByYear W20073348062012 @default.