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- W2007335215 abstract "Normal spleen cells were fractionated using equilibrium density gradient centrifugation. Three fractions were taken and the ability of those fractions to produce antibody-forming cells (PFC) in vitro was examined. The three fractions were distinct from each other in susceptibility to anti-θ serum, nutritional requirements, requirements for radiation-resistant cells, antigen dose optima, kinetics and participation in cell cycle. The results are interpreted as showing a differentiation series with the immunocompetent cells moving from the dense to the less dense region of the gradient following antigen stimulation. The correlation between steps in the rate of production of PFC's by unfractionated spleen cells and the contribution of each fraction to the total response are discussed." @default.
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- W2007335215 date "1971-09-01" @default.
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- W2007335215 title "The in vitro immune response to sheep erythrocytes by fractionated spleen cells: Biological and immunological differences" @default.
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- W2007335215 doi "https://doi.org/10.1016/0022-1759(71)90004-4" @default.
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