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- W2007342102 abstract "The diagnosis of pre-eruptive varicella cerebellitis is usually based on a history of exposure and thus depends on a subjective clinical assessment. The confirmation of the diagnosis has traditionally depended on the development of skin manifestations of varicella and on varicella-zoster antibody seroconversion. Confirming the diagnosis of pre-eruptive cerebellar ataxia or encephalitis early in the course of a viral infection may save the patient unnecessary tests, procedures, or attempts at therapeutic intervention. A patient is reported in whom, after clinically suspecting a diagnosis of pre-eruptive varicella cerebellitis, the diagnosis was confirmed by performing polymerase chain reaction analysis of varicella-zoster virus DNA in peripheral blood leukocytes and cerebrospinal fluid. The patient developed skin manifestations of varicella 5 days after the onset of neurologic symptoms and 15 days after known exposure. In some patients with pre-eruptive varicella cerebellitis, polymerase chain reaction may be extremely useful for rapid confirmation of the diagnosis." @default.
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- W2007342102 date "1993-11-01" @default.
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- W2007342102 title "Pre-eruptive varicella cerebellitis confirmed by PCR" @default.
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- W2007342102 doi "https://doi.org/10.1016/0887-8994(93)90032-8" @default.
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