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- W2007369554 abstract "A vancomycin aglycon analogue that possesses a reduced C-ring and an intact E-ring chloride was prepared and its antimicrobial activity towards Staphylococcus aureus and binding affinity to model cell wall ligands were established. Comparison of the derivative with a series of vancomycin aglycon analogues that possess and lack the chloro substituents on the aryl C- and E-rings defines the impact and further refines the role the C-ring chloride plays in promoting both target binding affinity and binding selectivity for d-Ala-d-Ala and its impact on antimicrobial activity." @default.
- W2007369554 created "2016-06-24" @default.
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- W2007369554 date "2013-09-01" @default.
- W2007369554 modified "2023-10-17" @default.
- W2007369554 title "Investigation into the functional impact of the vancomycin C-ring aryl chloride" @default.
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- W2007369554 doi "https://doi.org/10.1016/j.bmcl.2013.06.080" @default.
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