FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007377445> ?p ?o ?g. }

• W2007377445 endingPage "1556" @default.
• W2007377445 startingPage "1550" @default.
• W2007377445 abstract "Bronchiolitis obliterans syndrome (BOS) remains the primary factor limiting successful lung transplantation. In asthma and lung transplantation BOS-increased sub-mucosal vascularity has been shown to contribute to airflow limitation. Vascularity has 2 components: sprouting angiogenesis (more vessels) and microvascular enlargement (larger vessels). We hypothesized that the lack of a reanastomosed bronchial arterial blood supply at the time of transplant might stimulate angiogenesis and be a risk factor for subsequent BOS.Twenty-seven initially stable lung transplant recipients (BOS 0) were recruited at 148 +/- 80 days post-transplant and underwent clinical and bronchoscopic longitudinal follow-up for at least 3 years. Eight remained stable and BOS developed in 19. Nine normal controls were also recruited. Airway vasculature was examined immunohistochemically in endobronchial biopsy (EBB) specimens with collagen IV antibody, quantified by computer image analysis, and expressed as average vessel size, vessel number, and overall vascularity. The effects of demographic, clinical, bronchoalveolar lavage (BAL), and EBB variables on airway vasculature were analyzed in a multivariate model.No significant differences in airway vascularity were found between stable and BOS lung transplant recipients cross-sectionally or longitudinally. However, both lung transplant groups at baseline showed significantly greater airway vascularity compared with normal controls (p < .05). Multivariate analysis suggested that the percentage of BAL CD3+ cells and acute rejection are the most influential variables on airway vasculature.This study suggests early and persistent airway vasculature changes occur in lung transplant recipients, mainly manifested as microvascular enlargement. Potentially this baseline change contributes to airway obstruction and also puts all lung transplant recipients at risk for further exponential loss of airway caliber with any subsequent airway inflammatory insult." @default.
• W2007377445 created "2016-06-24" @default.
• W2007377445 creator A5009735497 @default.
• W2007377445 creator A5010661271 @default.
• W2007377445 creator A5046719540 @default.
• W2007377445 creator A5047620686 @default.
• W2007377445 creator A5052284514 @default.
• W2007377445 creator A5064787465 @default.
• W2007377445 creator A5085391910 @default.
• W2007377445 creator A5086310366 @default.
• W2007377445 date "2005-10-01" @default.
• W2007377445 modified "2023-09-25" @default.
• W2007377445 title "Airway Vascular Changes After Lung Transplant: Potential Contribution to the Pathophysiology of Bronchiolitis Obliterans Syndrome" @default.
• W2007377445 cites W1996195442 @default.
• W2007377445 cites W2015290201 @default.
• W2007377445 cites W2015416175 @default.
• W2007377445 cites W2017245391 @default.
• W2007377445 cites W2025564233 @default.
• W2007377445 cites W2033710219 @default.
• W2007377445 cites W2038436322 @default.
• W2007377445 cites W2039721686 @default.
• W2007377445 cites W2050020592 @default.
• W2007377445 cites W2052427882 @default.
• W2007377445 cites W2059522297 @default.
• W2007377445 cites W2068045591 @default.
• W2007377445 cites W2107855787 @default.
• W2007377445 cites W2124218821 @default.
• W2007377445 cites W2129379317 @default.
• W2007377445 cites W2132227824 @default.
• W2007377445 cites W2140667296 @default.
• W2007377445 cites W2159497838 @default.
• W2007377445 cites W2160926771 @default.
• W2007377445 cites W2170800315 @default.
• W2007377445 cites W4229829133 @default.
• W2007377445 cites W4250319062 @default.
• W2007377445 doi "https://doi.org/10.1016/j.healun.2004.11.008" @default.
• W2007377445 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16210129" @default.
• W2007377445 hasPublicationYear "2005" @default.
• W2007377445 type Work @default.
• W2007377445 sameAs 2007377445 @default.
• W2007377445 citedByCount "29" @default.
• W2007377445 countsByYear W20073774452013 @default.
• W2007377445 countsByYear W20073774452014 @default.
• W2007377445 countsByYear W20073774452015 @default.
• W2007377445 countsByYear W20073774452016 @default.
• W2007377445 countsByYear W20073774452018 @default.
• W2007377445 countsByYear W20073774452020 @default.
• W2007377445 countsByYear W20073774452022 @default.
• W2007377445 countsByYear W20073774452023 @default.
• W2007377445 crossrefType "journal-article" @default.
• W2007377445 hasAuthorship W2007377445A5009735497 @default.
• W2007377445 hasAuthorship W2007377445A5010661271 @default.
• W2007377445 hasAuthorship W2007377445A5046719540 @default.
• W2007377445 hasAuthorship W2007377445A5047620686 @default.
• W2007377445 hasAuthorship W2007377445A5052284514 @default.
• W2007377445 hasAuthorship W2007377445A5064787465 @default.
• W2007377445 hasAuthorship W2007377445A5085391910 @default.
• W2007377445 hasAuthorship W2007377445A5086310366 @default.
• W2007377445 hasConcept C105922876 @default.
• W2007377445 hasConcept C126322002 @default.
• W2007377445 hasConcept C141071460 @default.
• W2007377445 hasConcept C142724271 @default.
• W2007377445 hasConcept C178596483 @default.
• W2007377445 hasConcept C2776739411 @default.
• W2007377445 hasConcept C2777714996 @default.
• W2007377445 hasConcept C2778821649 @default.
• W2007377445 hasConcept C2780394083 @default.
• W2007377445 hasConcept C2781448352 @default.
• W2007377445 hasConcept C2911091166 @default.
• W2007377445 hasConcept C534529494 @default.
• W2007377445 hasConcept C71924100 @default.
• W2007377445 hasConceptScore W2007377445C105922876 @default.
• W2007377445 hasConceptScore W2007377445C126322002 @default.
• W2007377445 hasConceptScore W2007377445C141071460 @default.
• W2007377445 hasConceptScore W2007377445C142724271 @default.
• W2007377445 hasConceptScore W2007377445C178596483 @default.
• W2007377445 hasConceptScore W2007377445C2776739411 @default.
• W2007377445 hasConceptScore W2007377445C2777714996 @default.
• W2007377445 hasConceptScore W2007377445C2778821649 @default.
• W2007377445 hasConceptScore W2007377445C2780394083 @default.
• W2007377445 hasConceptScore W2007377445C2781448352 @default.
• W2007377445 hasConceptScore W2007377445C2911091166 @default.
• W2007377445 hasConceptScore W2007377445C534529494 @default.
• W2007377445 hasConceptScore W2007377445C71924100 @default.
• W2007377445 hasIssue "10" @default.
• W2007377445 hasLocation W20073774451 @default.
• W2007377445 hasLocation W20073774452 @default.
• W2007377445 hasOpenAccess W2007377445 @default.
• W2007377445 hasPrimaryLocation W20073774451 @default.
• W2007377445 hasRelatedWork W1006981286 @default.
• W2007377445 hasRelatedWork W1966396484 @default.
• W2007377445 hasRelatedWork W2002323163 @default.
• W2007377445 hasRelatedWork W2007377445 @default.
• W2007377445 hasRelatedWork W2053919545 @default.
• W2007377445 hasRelatedWork W2114266983 @default.
• W2007377445 hasRelatedWork W2403471041 @default.
• W2007377445 hasRelatedWork W2404853076 @default.
• W2007377445 hasRelatedWork W2407246661 @default.

• next