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- W2007378891 abstract "A new scalarane-type pentacyclic sesterterpene, sesterstatin 7 (1), was isolated from the Red Sea sponge Hyrtios erecta, together with 16-epi-scalarolbutenolide (2), 25-dehydroxy-12-epi-deacetylscalarin (3), 3-acetylsesterstatin 1 (4), and 21-acetoxydeoxyscalarin. The structure of 1 was elucidated by spectroscopic data interpretation. Sesterstatin 7 (1) showed 63% inhibition of Mycobacterium tuberculosis (H37Rv) at a concentration of 6.25 μg/mL. Compound 2 displayed moderate inhibitory activity, while 3 and 4 were weakly active against the same biological target." @default.
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- W2007378891 date "2005-11-10" @default.
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- W2007378891 title "Antimycobacterial Scalarane-Based Sesterterpenes from the Red Sea Sponge <i>Hyrtios </i><i>e</i><i>recta</i>" @default.
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- W2007378891 doi "https://doi.org/10.1021/np0502645" @default.
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