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• W2007380911 abstract "Tritonia pedal ganglion peptides (TPeps) are a trio of pentadecapeptides isolated from the brain of the nudibranch Tritonia diomedea. TPeps have been shown both to increase the beating rate of ciliated cells of Tritonia and to accelerate heart contractions in the mollusc Clione limacina. Here we examine the immunocytochemical distribution of TPeps in the Tritonia central nervous system. We found the brain and buccal ganglia to be rich sources of TPep immunoreactivity. Specific cells in both structures, some of them previously identified, were immunoreactive. Moreover, immunoreactive fibers were seen connecting ganglia and exiting almost all the major nerves. In the brain, we found that the paired, ciliated statocysts apparently receive TPep innervation. In addition, we observed unstained cell bodies in each buccal ganglion with extensive TPep immunoreactive projections surrounding their somata and primary neurites. Similar projections were not observed in the brain. We also compared the TPep immunoreactivity with that of SCPb in the buccal ganglia. We observed many neurons and processes that were immunoreactive to both peptides. One neuron that contains both TPep- and SCPb-like peptides (B12) has an identified role in the Tritonia feeding network. Together, these findings suggest that TPeps may play an active role in the central nervous system of Tritonia as neurotransmitters modulating orientation, swimming, and feeding. J. Comp. Neurol. 425:1–9, 2000. © 2000 Wiley-Liss, Inc." @default.
• W2007380911 created "2016-06-24" @default.
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• W2007380911 date "2000-01-01" @default.
• W2007380911 modified "2023-09-30" @default.
• W2007380911 title "Immunocytochemical localization of pedal peptide in the central nervous system of the gastropod molluscTritonia diomedea" @default.
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• W2007380911 doi "https://doi.org/10.1002/1096-9861(20000911)425:1<1::aid-cne1>3.0.co;2-y" @default.
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