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- W2007393310 abstract "In Brief Purpose: To report the surgical outcome, histopathology, immunohistochemistry, and optical coherence tomographic findings in a case of bilateral combined hamartoma of retina and retinal pigment epithelium. Method: Bilateral heterologous plasmin-assisted lens-sparing vitrectomy was performed. The surgical specimen underwent histopathological and immunohistochemical analysis. Patient: An 18-month-old male child with bilateral combined hamartoma of the retina and retinal pigment epithelium. Results: After surgery, structural improvement (optical coherence tomography) and improved visual function were noted. Immunohistochemistry was positive for astrocytic markers and negative for others. Discussion: Plasmin-assisted vitrectomy and membrane peeling in this child with bilateral combined hamartoma resulted in a marked improvement in the clinical and topographical appearance in both eyes and significantly improved visual function. The prospect of hamartoma recurrence is not a contraindication to surgical management. Immunohistochemically, the peeled epiretinal tissue showed characteristics of astrocytic origin providing insight into the possible source and structure of these membranes. An 18-month-old male child underwent bilateral plasmin-assisted vitrectomy for epiretinal membranes with tractional detachment due to bilateral combined hamartoma of the retina and retinal pigment epithelium. Histopathological and immunohistochemistry findings of the excised lesion are discussed." @default.
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- W2007393310 date "2009-01-01" @default.
- W2007393310 modified "2023-09-25" @default.
- W2007393310 title "PLASMIN-ASSISTED VITRECTOMY FOR BILATERAL COMBINED HAMARTOMA OF THE RETINA AND RETINAL PIGMENT EPITHELIUM: HISTOPATHOLOGY, IMMUNOHISTOCHEMISTRY, AND OPTICAL COHERENCE TOMOGRAPHY" @default.
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- W2007393310 doi "https://doi.org/10.1097/icb.0b013e318185ea69" @default.
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