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• W2007407619 abstract "The effects of theta burst stimulation (TBS) have been extensively investigated in primary motor cortex, where it leads to long-lasting LTP/LTD-like effects on synaptic plasticity. This study aimed to extend these observations to sensory cortex.Fourteen healthy subjects participated in the study. Conditioning 600-pulse intermittent TBS (iTBS) and continuous TBS (cTBS) were delivered to left somatosensory cortex (S1) with an intensity of 80% active motor threshold. Somatosensory evoked potentials (SEPs) were evoked by median nerve electrical stimulation at right wrist. High frequency oscillations (HFOs) were obtained by digital filtering of original SEPs and divided into early and late subcomponents, relative to N20(peak) latency.Repeated-measures ANOVA showed that iTBS facilitated N20(onset)-N20(peak) at 15min and N20(peak)-P25 at 15 and 30min after conditioning, whereas cTBS did not. iTBS left the early and late HFOs unchanged. Conversely, cTBS facilitated the early HFOs, whereas it inhibited the late HFOs at 15min after conditioning.S1-iTBS facilitated SEPs without changes in HFOs whereas cTBS modulated early and late HFOs without changes in SEPs.S1-TBS produces lasting changes in the excitability of intracortical circuits generating SEPs and HFOs differentially through mechanisms of LTP/LTD-like synaptic plasticity." @default.
• W2007407619 created "2016-06-24" @default.
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• W2007407619 creator A5063393873 @default.
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• W2007407619 date "2010-12-01" @default.
• W2007407619 modified "2023-10-03" @default.
• W2007407619 title "Somatosensory evoked potentials and high frequency oscillations are differently modulated by theta burst stimulation over primary somatosensory cortex in humans" @default.
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• W2007407619 doi "https://doi.org/10.1016/j.clinph.2010.05.014" @default.
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