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- W2007409831 abstract "Human DNA enriched in repetitive sequences specifically bound to a component(s) in purified preparations of rat brain protein kinase C (PKC). DNA which bound to protein was cloned in pUC-19 and one clone characterized as containing an approx. 140 bp insert. The band containing this insert (separated by acrylamide gel electrophoresis) was lost when the DNA was incubated with purified PKC preparations. Thus a protein in relatively pure PKC preparations is a sequence-selective DNA-binding protein. The results raise the possibility that PKC or a fragment of PKC binds selectively to specific DNA sequences." @default.
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- W2007409831 date "1988-10-01" @default.
- W2007409831 modified "2023-10-12" @default.
- W2007409831 title "DNA-binding proteins in protein kinase C preparations" @default.
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- W2007409831 doi "https://doi.org/10.1016/s0006-291x(88)80828-3" @default.
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