FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007412036> ?p ?o ?g. }

• W2007412036 endingPage "2209" @default.
• W2007412036 startingPage "2204" @default.
• W2007412036 abstract "Background. With resected tumor tissue from 84 patients with lung cancer, the expression of glutathione peroxidase (GPX), glutathione reductase (GR), proliferating cell nuclear antigen (PCNA), and epidermal growth factor receptor (EGFR) was examined in relation to cisdiamminedichloroplatinum (CDDP) sensitivity. Methods. The CDDP sensitivity was assessed from an increase of cells in the S-phase or G2M-phase by a DNA histogram after the tumor cells were incubated in a CDDP solution. The expression of GPX, GR, PCNA, and EGFR for each tumor was studied with an indirect immunoperoxidase technique on paraffin-embedded tissues. Results. The percentage of patients sensitive to CDDP according to the histologic type was 86% for small cell carcinomas, 40% for large cell carcinomas, 31% for squamous cell carcinomas, and 6% for adenocarcinomas. There was an inverse relationship between CDDP sensitivity and the frequency of GPX and GR expression, and both were significantly different among histologic types. The GPX and GR expression was significantly lower in the CDDP-sensitive group than in the resistant group (P < 0.01). However, the expression of PCNA and EGFR was significantly lower in the sensitive group in non–small cell carcinomas and squamous cell carcinomas (P < 0.05). Conclusions. From the above findings, an immunohistochemical study of these antigens may be useful for predicting CDDP sensitivity in lung cancer." @default.
• W2007412036 created "2016-06-24" @default.
• W2007412036 creator A5003838574 @default.
• W2007412036 creator A5015749650 @default.
• W2007412036 creator A5030154468 @default.
• W2007412036 creator A5056985388 @default.
• W2007412036 creator A5071574484 @default.
• W2007412036 date "1993-04-01" @default.
• W2007412036 modified "2023-09-24" @default.
• W2007412036 title "Immunohistochemical study of glutathione-related enzymes and proliferative antigens in lung cancer. Relation to cisplatin sensitivity" @default.
• W2007412036 cites W1565544493 @default.
• W2007412036 cites W1968018484 @default.
• W2007412036 cites W1972562299 @default.
• W2007412036 cites W1974552330 @default.
• W2007412036 cites W1978515600 @default.
• W2007412036 cites W2011743008 @default.
• W2007412036 cites W2012120642 @default.
• W2007412036 cites W2025163738 @default.
• W2007412036 cites W2034252405 @default.
• W2007412036 cites W2037480691 @default.
• W2007412036 cites W2040577258 @default.
• W2007412036 cites W2042320307 @default.
• W2007412036 cites W2070077921 @default.
• W2007412036 cites W2076031397 @default.
• W2007412036 cites W2079161724 @default.
• W2007412036 cites W2086543254 @default.
• W2007412036 doi "https://doi.org/10.1002/1097-0142(19930401)71:7<2204::aid-cncr2820710707>3.0.co;2-o" @default.
• W2007412036 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8095847" @default.
• W2007412036 hasPublicationYear "1993" @default.
• W2007412036 type Work @default.
• W2007412036 sameAs 2007412036 @default.
• W2007412036 citedByCount "47" @default.
• W2007412036 countsByYear W20074120362014 @default.
• W2007412036 countsByYear W20074120362015 @default.
• W2007412036 countsByYear W20074120362017 @default.
• W2007412036 countsByYear W20074120362018 @default.
• W2007412036 countsByYear W20074120362019 @default.
• W2007412036 countsByYear W20074120362020 @default.
• W2007412036 countsByYear W20074120362022 @default.
• W2007412036 countsByYear W20074120362023 @default.
• W2007412036 crossrefType "journal-article" @default.
• W2007412036 hasAuthorship W2007412036A5003838574 @default.
• W2007412036 hasAuthorship W2007412036A5015749650 @default.
• W2007412036 hasAuthorship W2007412036A5030154468 @default.
• W2007412036 hasAuthorship W2007412036A5056985388 @default.
• W2007412036 hasAuthorship W2007412036A5071574484 @default.
• W2007412036 hasBestOaLocation W20074120361 @default.
• W2007412036 hasConcept C121608353 @default.
• W2007412036 hasConcept C126322002 @default.
• W2007412036 hasConcept C128102431 @default.
• W2007412036 hasConcept C142724271 @default.
• W2007412036 hasConcept C147483822 @default.
• W2007412036 hasConcept C1491633281 @default.
• W2007412036 hasConcept C159654299 @default.
• W2007412036 hasConcept C203014093 @default.
• W2007412036 hasConcept C204232928 @default.
• W2007412036 hasConcept C2775838275 @default.
• W2007412036 hasConcept C2776151105 @default.
• W2007412036 hasConcept C2776256026 @default.
• W2007412036 hasConcept C2776694085 @default.
• W2007412036 hasConcept C2778239845 @default.
• W2007412036 hasConcept C2778760513 @default.
• W2007412036 hasConcept C2779438470 @default.
• W2007412036 hasConcept C34688535 @default.
• W2007412036 hasConcept C502942594 @default.
• W2007412036 hasConcept C542903549 @default.
• W2007412036 hasConcept C54355233 @default.
• W2007412036 hasConcept C71924100 @default.
• W2007412036 hasConcept C86803240 @default.
• W2007412036 hasConceptScore W2007412036C121608353 @default.
• W2007412036 hasConceptScore W2007412036C126322002 @default.
• W2007412036 hasConceptScore W2007412036C128102431 @default.
• W2007412036 hasConceptScore W2007412036C142724271 @default.
• W2007412036 hasConceptScore W2007412036C147483822 @default.
• W2007412036 hasConceptScore W2007412036C1491633281 @default.
• W2007412036 hasConceptScore W2007412036C159654299 @default.
• W2007412036 hasConceptScore W2007412036C203014093 @default.
• W2007412036 hasConceptScore W2007412036C204232928 @default.
• W2007412036 hasConceptScore W2007412036C2775838275 @default.
• W2007412036 hasConceptScore W2007412036C2776151105 @default.
• W2007412036 hasConceptScore W2007412036C2776256026 @default.
• W2007412036 hasConceptScore W2007412036C2776694085 @default.
• W2007412036 hasConceptScore W2007412036C2778239845 @default.
• W2007412036 hasConceptScore W2007412036C2778760513 @default.
• W2007412036 hasConceptScore W2007412036C2779438470 @default.
• W2007412036 hasConceptScore W2007412036C34688535 @default.
• W2007412036 hasConceptScore W2007412036C502942594 @default.
• W2007412036 hasConceptScore W2007412036C542903549 @default.
• W2007412036 hasConceptScore W2007412036C54355233 @default.
• W2007412036 hasConceptScore W2007412036C71924100 @default.
• W2007412036 hasConceptScore W2007412036C86803240 @default.
• W2007412036 hasIssue "7" @default.
• W2007412036 hasLocation W20074120361 @default.
• W2007412036 hasLocation W20074120362 @default.
• W2007412036 hasOpenAccess W2007412036 @default.
• W2007412036 hasPrimaryLocation W20074120361 @default.
• W2007412036 hasRelatedWork W2000495635 @default.
• W2007412036 hasRelatedWork W2007460616 @default.

• next