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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007441995> ?p ?o ?g. }

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• W2007441995 abstract "Responses of dorsal horn neurons to iontophoretically administered substance P were attenuated by iontophoretically applied 5-hydroxytryptamine (5-HT). This occurred even when 5-HT alone had no effect on the excitability of the cell. 5-HT did not attenuated responses to iontophoretic application of glutamate. It has been suggested that 5-HT presynaptically inhibits the nociceptive afferents but direct application of 5-HT whilst recording the polarisation of primary afferents in vivo failed to confirm this postulate. These results cannot be explained by a presynaptic inhibition of primary afferents by 5-HT and it is suggested that 5-HT is either acting directly on the substance P receptor or on the receptor-excitation coupling mechanism." @default.
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• W2007441995 date "1981-08-01" @default.
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• W2007441995 title "5-Hydroxytryptamine reduces substabce P responses on dorsal horn interneurones: a possible interaction of neurotransmitters" @default.
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• W2007441995 doi "https://doi.org/10.1016/0006-8993(81)90018-4" @default.
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