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- W2007449327 abstract "Policondrite recidivante é uma condição rara, imunomediada, caracterizada por episódios de inflamação de estruturas cartilaginosas, principalmente orelhas, nariz, articulações e sistema respiratório. Acomete também estruturas ricas em proteoglicanos como olhos, coração, vasos sanguíneos e ouvido interno. Em torno de 1/3 dos casos apresentam associação com outras doenças como vasculites sistêmicas, doenças do tecido conectivo ou síndrome mielodisplásica. Desordens do ouvido interno ocorrem em 40%‐50% dos pacientes. Perda auditiva profunda é rara. O objetivo do estudo foi descrever o caso de uma paciente com diagnóstico de policondrite recidivante associado à perda auditiva severa bilateral e manifestações clínicas de vasculite sistêmica. Este trabalho reforça a importância do diagnóstico precoce e do tratamento imediato em caso de manifestações severas da doença. Relapsing polychondritis is an uncommon, immune‐mediated condition characterized by episodes of inflammation of cartilaginous structures, especially the ears, nose, joints and respiratory tract. RP also affects proteoglycan‐rich structures such as the eyes, heart, blood vessels and inner ear. Around one third of cases are associated with other diseases such as vasculitides, connective tissue diseases or myelodysplastic syndrome. Disorders of the inner ear occur in 40‐50% of patients. Profound hearing loss is rare. The aim of this study was to describe the case of a patient with relapsing polychondritis associated with severe bilateral hearing loss and clinical manifestations of systemic vasculitis. This study reinforces the importance of an early diagnosis and immediate treatment in case of severe manifestations of the disease." @default.
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- W2007449327 date "2015-03-01" @default.
- W2007449327 modified "2023-09-24" @default.
- W2007449327 title "Policondrite recidivante com perda auditiva severa" @default.
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- W2007449327 doi "https://doi.org/10.1016/j.rbr.2014.03.030" @default.
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