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- W2007449345 abstract "Recent studies indicate that angiogenesis may be involved in the pathogenesis of certain hematological malignancies. However as far as B-cell chronic lymphocytic leukemia (CLL) is concerned, current data dealing with the evaluation of bone marrow (BM) microvessel density, a marker of angiogenesis grade, do not as yet provide definitive results. It is now clear that the mRNA isoforms VEGF121 and VEGF 165 are expressed by B-CLL cells. In addition, low cellular and high serum levels of VEGF correlated with a poor clinical outcome. Although these data do not as yet show that angiogenesis is essential for B-CLL, it may indeed be relevant in the leukemic process so characteristic of this diseases." @default.
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- W2007449345 date "2001-01-01" @default.
- W2007449345 modified "2023-09-23" @default.
- W2007449345 title "Angiogenesis in B-Cell Chronic Lymphocytic Leukemia: Methods of Study, Clinical Significance and Prognostic Implications" @default.
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- W2007449345 doi "https://doi.org/10.3109/10428190109099320" @default.
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