FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007456650> ?p ?o ?g. }

• W2007456650 endingPage "4778" @default.
• W2007456650 startingPage "4767" @default.
• W2007456650 abstract "The strategy of phospholipid-based biomimicry has been used to molecularly engineer poly(2-hydroxyethyl methacrylate) [p(HEMA)]-based hydrogels for improved in vitro and potential in vivo biocompatibility. Two methacrylate-based monomers, poly(ethylene glycol) (200) monomethacrylate (PEGMA) and 2-methacryloyloxyethyl phosphorylcholine (MPC), were incorporated at varying mole fractions of 0.0–0.5 mol% PEGMA and 0–10 mol% MPC respectively, into 3 mol% tetraethyleneglycol diacrylate (TEGDA) cross-linked p(HEMA) networks. Upon hydration of these engineered hydrogels, a reduction in receding contact angle from 22±1.2° for p(HEMA) to 8±2.7° for p(HEMA) containing 0.5:10 mol% PEGMA:MPC was observed, reflecting the significant increase in surface hydrophilicity with increasing PEGMA and MPC content upon prolonged hydration. Hydrogels containing MPC showed a temporal increase in hydrophilicity following continuous immersion in DI water over 5 days. Hydrogels containing 0.5 mol% PEGMA and MPC in the range of 5–10 mol% displayed reduced protein adsorption when incubated with the common extracellular matrix proteins; fibronectin, collagen or laminin, producing up to 64% less protein adsorption compared to p(HEMA). Compositional optima for cell viability and proliferation established from two-factor Central Composite design analysis of human muscle fibroblasts cultured on these hydrogels suggest that those containing PEGMA between 0.3 and 0.5 mol% and MPC levels around 5–10 mol% exhibit desirable characteristics for implant material coatings—high viability (>80%) with low proliferation (<40%), confirming a lack of cytotoxicity." @default.
• W2007456650 created "2016-06-24" @default.
• W2007456650 creator A5005237164 @default.
• W2007456650 creator A5027269429 @default.
• W2007456650 creator A5030939891 @default.
• W2007456650 creator A5040411835 @default.
• W2007456650 date "2005-08-01" @default.
• W2007456650 modified "2023-10-15" @default.
• W2007456650 title "Molecularly engineered p(HEMA)-based hydrogels for implant biochip biocompatibility" @default.
• W2007456650 cites W1245876582 @default.
• W2007456650 cites W1594096671 @default.
• W2007456650 cites W1978601259 @default.
• W2007456650 cites W1985896743 @default.
• W2007456650 cites W1986023680 @default.
• W2007456650 cites W1988575521 @default.
• W2007456650 cites W1993494015 @default.
• W2007456650 cites W1995851716 @default.
• W2007456650 cites W1997483646 @default.
• W2007456650 cites W2001909877 @default.
• W2007456650 cites W2005064772 @default.
• W2007456650 cites W2008215555 @default.
• W2007456650 cites W2010828967 @default.
• W2007456650 cites W2014058701 @default.
• W2007456650 cites W2019875670 @default.
• W2007456650 cites W2022872391 @default.
• W2007456650 cites W2030795397 @default.
• W2007456650 cites W2036532945 @default.
• W2007456650 cites W2041322047 @default.
• W2007456650 cites W2049929874 @default.
• W2007456650 cites W2050826685 @default.
• W2007456650 cites W2055387044 @default.
• W2007456650 cites W2055926917 @default.
• W2007456650 cites W2061929484 @default.
• W2007456650 cites W2063619476 @default.
• W2007456650 cites W2064412313 @default.
• W2007456650 cites W2068349731 @default.
• W2007456650 cites W2068640368 @default.
• W2007456650 cites W2072797273 @default.
• W2007456650 cites W2079711588 @default.
• W2007456650 cites W2085767500 @default.
• W2007456650 cites W2091833774 @default.
• W2007456650 cites W2092232077 @default.
• W2007456650 cites W2123697633 @default.
• W2007456650 cites W2137411554 @default.
• W2007456650 cites W2139455476 @default.
• W2007456650 cites W2160147504 @default.
• W2007456650 cites W2161158799 @default.
• W2007456650 cites W2164441440 @default.
• W2007456650 cites W2166224995 @default.
• W2007456650 doi "https://doi.org/10.1016/j.biomaterials.2005.01.031" @default.
• W2007456650 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15763256" @default.
• W2007456650 hasPublicationYear "2005" @default.
• W2007456650 type Work @default.
• W2007456650 sameAs 2007456650 @default.
• W2007456650 citedByCount "170" @default.
• W2007456650 countsByYear W20074566502012 @default.
• W2007456650 countsByYear W20074566502013 @default.
• W2007456650 countsByYear W20074566502014 @default.
• W2007456650 countsByYear W20074566502015 @default.
• W2007456650 countsByYear W20074566502016 @default.
• W2007456650 countsByYear W20074566502017 @default.
• W2007456650 countsByYear W20074566502018 @default.
• W2007456650 countsByYear W20074566502019 @default.
• W2007456650 countsByYear W20074566502020 @default.
• W2007456650 countsByYear W20074566502021 @default.
• W2007456650 countsByYear W20074566502022 @default.
• W2007456650 countsByYear W20074566502023 @default.
• W2007456650 crossrefType "journal-article" @default.
• W2007456650 hasAuthorship W2007456650A5005237164 @default.
• W2007456650 hasAuthorship W2007456650A5027269429 @default.
• W2007456650 hasAuthorship W2007456650A5030939891 @default.
• W2007456650 hasAuthorship W2007456650A5040411835 @default.
• W2007456650 hasConcept C108586683 @default.
• W2007456650 hasConcept C127413603 @default.
• W2007456650 hasConcept C132050475 @default.
• W2007456650 hasConcept C136229726 @default.
• W2007456650 hasConcept C150394285 @default.
• W2007456650 hasConcept C159985019 @default.
• W2007456650 hasConcept C166940927 @default.
• W2007456650 hasConcept C178790620 @default.
• W2007456650 hasConcept C185592680 @default.
• W2007456650 hasConcept C188027245 @default.
• W2007456650 hasConcept C191897082 @default.
• W2007456650 hasConcept C192562407 @default.
• W2007456650 hasConcept C2777230088 @default.
• W2007456650 hasConcept C2777516009 @default.
• W2007456650 hasConcept C42360764 @default.
• W2007456650 hasConcept C49892992 @default.
• W2007456650 hasConcept C521977710 @default.
• W2007456650 hasConcept C71924100 @default.
• W2007456650 hasConcept C88001094 @default.
• W2007456650 hasConceptScore W2007456650C108586683 @default.
• W2007456650 hasConceptScore W2007456650C127413603 @default.
• W2007456650 hasConceptScore W2007456650C132050475 @default.
• W2007456650 hasConceptScore W2007456650C136229726 @default.
• W2007456650 hasConceptScore W2007456650C150394285 @default.
• W2007456650 hasConceptScore W2007456650C159985019 @default.
• W2007456650 hasConceptScore W2007456650C166940927 @default.

• next