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- W2007460057 abstract "The process development of a peptide coupling with CDI is discussed. Various solvents, addition orders, stoichiometries, and reaction temperatures were investigated. A reliable crystallization procedure was also developed. The new process was piloted to provide 342 kg of product in two batches with an average 85% yield and 99% assay." @default.
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- W2007460057 date "2008-11-26" @default.
- W2007460057 modified "2023-10-17" @default.
- W2007460057 title "Pilot-Plant Preparation of an α<sub>v</sub>β<sub>3</sub> Integrin Antagonist: Process Development of a Carbonyldiimidazole Peptide Coupling" @default.
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- W2007460057 doi "https://doi.org/10.1021/op8002213" @default.
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