FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007477462> ?p ?o ?g. }

• W2007477462 endingPage "954" @default.
• W2007477462 startingPage "949" @default.
• W2007477462 abstract "Objectives To report the experiences on preimplantation genetic diagnosis (PGD) in couples at risk for ß-thalassaemia in Sardinia. Methods 23 couples at risk for ß-thalassaemia were included in the PGD programme with a total of 42 cycles performed. Among these, 11 couples were fertile, while the remaining 12 had associated fertility problems. In vitro Fertilization (IVF), PGD and prenatal genetic molecular confirmation protocols and results are reported. Results All the patients followed the protocol of ovarian stimulation, oocyte retrieval, intracytoplasmic sperm injection (ICSI), embryo biopsy and genetic analysis. A total of 272 oocytes were fertilized in the regular way, and embryo biopsy was performed on 202 embryos. Out of these 202 embryos, 192 (95%) were successful. The genetic diagnosis was performed on 150 embryos (78.1%). Ninety-eight were identified as unaffected and 75 were transferred in 31 cycles. In the infertile patient group, two biochemical pregnancies (11.1% per transfer), in the fertile patient group, four clinical pregnancies, two twin and two singleton pregnancies (30.8% per transfer), were obtained. The genetic molecular results were confirmed in all pregnancies by first-trimester chorionic villus sampling (CVS). Conclusion Our study shows that PGD for ß-thalassaemia is an available procedure for couples who wish to avoid termination of pregnancy, except in cases where the IVF cycle efficiency is very poor. Copyright © 2004 John Wiley & Sons, Ltd." @default.
• W2007477462 created "2016-06-24" @default.
• W2007477462 creator A5005292069 @default.
• W2007477462 creator A5020650044 @default.
• W2007477462 creator A5026950818 @default.
• W2007477462 creator A5028680053 @default.
• W2007477462 creator A5039160962 @default.
• W2007477462 creator A5070867622 @default.
• W2007477462 creator A5082180670 @default.
• W2007477462 creator A5086600772 @default.
• W2007477462 creator A5091294870 @default.
• W2007477462 date "2004-12-15" @default.
• W2007477462 modified "2023-09-27" @default.
• W2007477462 title "Preimplantation genetic diagnosis for β-thalassaemia: the Sardinian experience" @default.
• W2007477462 cites W1488899745 @default.
• W2007477462 cites W1977302767 @default.
• W2007477462 cites W1991926245 @default.
• W2007477462 cites W1992788166 @default.
• W2007477462 cites W2004694926 @default.
• W2007477462 cites W2030895549 @default.
• W2007477462 cites W2033362372 @default.
• W2007477462 cites W2049071313 @default.
• W2007477462 cites W2052865863 @default.
• W2007477462 cites W2060862558 @default.
• W2007477462 cites W2066672702 @default.
• W2007477462 cites W2095509709 @default.
• W2007477462 cites W2098785511 @default.
• W2007477462 cites W2116073351 @default.
• W2007477462 cites W2130616852 @default.
• W2007477462 cites W2131531401 @default.
• W2007477462 cites W2132145315 @default.
• W2007477462 cites W2133601595 @default.
• W2007477462 cites W2134373876 @default.
• W2007477462 cites W2137329890 @default.
• W2007477462 cites W2142172158 @default.
• W2007477462 cites W2160559979 @default.
• W2007477462 cites W2163324212 @default.
• W2007477462 cites W2258066394 @default.
• W2007477462 cites W2275985021 @default.
• W2007477462 cites W2321800574 @default.
• W2007477462 cites W2325585496 @default.
• W2007477462 cites W41238179 @default.
• W2007477462 cites W4254855656 @default.
• W2007477462 cites W4302354217 @default.
• W2007477462 cites W82694129 @default.
• W2007477462 doi "https://doi.org/10.1002/pd.1051" @default.
• W2007477462 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15614915" @default.
• W2007477462 hasPublicationYear "2004" @default.
• W2007477462 type Work @default.
• W2007477462 sameAs 2007477462 @default.
• W2007477462 citedByCount "22" @default.
• W2007477462 countsByYear W20074774622013 @default.
• W2007477462 countsByYear W20074774622014 @default.
• W2007477462 countsByYear W20074774622015 @default.
• W2007477462 countsByYear W20074774622018 @default.
• W2007477462 countsByYear W20074774622020 @default.
• W2007477462 countsByYear W20074774622021 @default.
• W2007477462 countsByYear W20074774622022 @default.
• W2007477462 countsByYear W20074774622023 @default.
• W2007477462 crossrefType "journal-article" @default.
• W2007477462 hasAuthorship W2007477462A5005292069 @default.
• W2007477462 hasAuthorship W2007477462A5020650044 @default.
• W2007477462 hasAuthorship W2007477462A5026950818 @default.
• W2007477462 hasAuthorship W2007477462A5028680053 @default.
• W2007477462 hasAuthorship W2007477462A5039160962 @default.
• W2007477462 hasAuthorship W2007477462A5070867622 @default.
• W2007477462 hasAuthorship W2007477462A5082180670 @default.
• W2007477462 hasAuthorship W2007477462A5086600772 @default.
• W2007477462 hasAuthorship W2007477462A5091294870 @default.
• W2007477462 hasConcept C131872663 @default.
• W2007477462 hasConcept C160099875 @default.
• W2007477462 hasConcept C16685009 @default.
• W2007477462 hasConcept C172680121 @default.
• W2007477462 hasConcept C196843134 @default.
• W2007477462 hasConcept C2776555163 @default.
• W2007477462 hasConcept C2778258057 @default.
• W2007477462 hasConcept C2778278907 @default.
• W2007477462 hasConcept C2778805741 @default.
• W2007477462 hasConcept C2779234561 @default.
• W2007477462 hasConcept C29456083 @default.
• W2007477462 hasConcept C512716672 @default.
• W2007477462 hasConcept C54355233 @default.
• W2007477462 hasConcept C71924100 @default.
• W2007477462 hasConcept C86803240 @default.
• W2007477462 hasConceptScore W2007477462C131872663 @default.
• W2007477462 hasConceptScore W2007477462C160099875 @default.
• W2007477462 hasConceptScore W2007477462C16685009 @default.
• W2007477462 hasConceptScore W2007477462C172680121 @default.
• W2007477462 hasConceptScore W2007477462C196843134 @default.
• W2007477462 hasConceptScore W2007477462C2776555163 @default.
• W2007477462 hasConceptScore W2007477462C2778258057 @default.
• W2007477462 hasConceptScore W2007477462C2778278907 @default.
• W2007477462 hasConceptScore W2007477462C2778805741 @default.
• W2007477462 hasConceptScore W2007477462C2779234561 @default.
• W2007477462 hasConceptScore W2007477462C29456083 @default.
• W2007477462 hasConceptScore W2007477462C512716672 @default.
• W2007477462 hasConceptScore W2007477462C54355233 @default.
• W2007477462 hasConceptScore W2007477462C71924100 @default.

• next