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- W2007482910 abstract "Conventional TB diagnosis continues to rely on smear microscopy, culture and chest radiography. Other non-conventional approaches include detection of immunological response and the search for biochemical markers. Cancer antigen 125 (Ca-125) was evaluated mainly in patients with extra pulmonary TB. This study was designed to detect the role of Ca-125 in differentiating pulmonary tuberculosis from other pulmonary infections. Also to determine the value of Ca-125 was an indicator of response to anti-tuberculous drugs. Eighty patients were included in the study, 27 with active pulmonary TB and 33 with other pulmonary infections. Twenty healthy volunteers were used as a control group. Measurement of serum Ca-125 was performed once in all groups, it was re-assayed after 4 months of anti-tuberculous drugs among patients with active pulmonary TB. There was a significant increase of Ca-125 among patients with active pulmonary TB than the other groups, which decrease significantly after anti-tuberculous drugs. The sensitivity and specificity of Ca-125 were found to be 81.4% and 95%, respectively, at a 34.6 U/ml cut-off point. Ca-125 can be a useful marker in differentiating pulmonary TB from other pulmonary infections and in assessment the response to anti-tuberculoussis drugs." @default.
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- W2007482910 date "2013-07-01" @default.
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- W2007482910 title "Role of cancer antigen 125 in active pulmonary tuberculosis" @default.
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- W2007482910 doi "https://doi.org/10.1016/j.ejcdt.2013.07.016" @default.
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