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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007483362> ?p ?o ?g. }

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• W2007483362 abstract "We designed and synthesized a novel series of phenylamino- and phenoxy-substituted pyrazolo[3,4-d]pyrimidine derivatives as GPR119 agonists. SAR studies indicated that electron-withdrawing substituents on the phenyl ring are important for potency and full efficacy. Compound 26 combined good potency with a promising pharmacokinetic profile in mice, and lowered the glucose excursion in mice in an oral glucose-tolerance test." @default.
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• W2007483362 date "2014-02-01" @default.
• W2007483362 modified "2023-09-24" @default.
• W2007483362 title "Discovery of pyrazolo[3,4-d]pyrimidine derivatives as GPR119 agonists" @default.
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• W2007483362 doi "https://doi.org/10.1016/j.bmcl.2013.12.063" @default.
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