FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007483903> ?p ?o ?g. }

• W2007483903 endingPage "1877" @default.
• W2007483903 startingPage "1873" @default.
• W2007483903 abstract "Anaplastic thyroid carcinoma can be difficult to diagnose because it does not show thyroid differentiation morphologically or immunohistochemically. Depending on the histologic variant, anaplastic thyroid carcinoma may be confused with sarcoma or squamous cell carcinoma of the head and neck. PAX8 is a transcription factor expressed in normal and neoplastic thyroid follicular epithelium and only a few other tissues. This restricted expression suggests that PAX8 staining could be useful when dealing with spindled or squamoid tumors of the neck. The purposes of this study were to determine the frequency of PAX8 staining in anaplastic thyroid carcinoma and to evaluate PAX8 immunohistochemistry as a means of distinguishing its squamoid variant from head and neck squamous cell carcinoma. PAX8 immunohistochemical staining was performed on 34 anaplastic thyroid carcinomas and 118 head and neck squamous cell carcinomas. PAX8 staining was present in 26 (76%) anaplastic thyroid carcinomas including 16 (100%) of 16 squamoid variants, 7 (58%) of 12 giant cell/pleomorphic variants, and 3 (50%) of 6 spindled variants. All head and neck squamous cell carcinomas were negative for PAX8. PAX8 expression is often retained in anaplastic thyroid carcinomas including the squamoid variant, but it is not expressed in head and neck squamous cancers. PAX8 staining is an excellent marker for carcinomas of follicular epithelial origin, including those carcinomas that are undifferentiated in other respects. The tissue specificity of PAX8 expression may be useful in resolving the differential diagnosis of anaplastic thyroid carcinoma such as the distinction between its squamoid variant and squamous cell carcinoma of the head and neck." @default.
• W2007483903 created "2016-06-24" @default.
• W2007483903 creator A5009195048 @default.
• W2007483903 creator A5021281217 @default.
• W2007483903 creator A5071072947 @default.
• W2007483903 date "2011-12-01" @default.
• W2007483903 modified "2023-10-18" @default.
• W2007483903 title "PAX8 immunostaining of anaplastic thyroid carcinoma: a reliable means of discerning thyroid origin for undifferentiated tumors of the head and neck" @default.
• W2007483903 cites W1567769659 @default.
• W2007483903 cites W1980794884 @default.
• W2007483903 cites W1992882239 @default.
• W2007483903 cites W2011746263 @default.
• W2007483903 cites W2015430536 @default.
• W2007483903 cites W2022394260 @default.
• W2007483903 cites W2040530124 @default.
• W2007483903 cites W2042596604 @default.
• W2007483903 cites W2045255183 @default.
• W2007483903 cites W2056142814 @default.
• W2007483903 cites W2074125591 @default.
• W2007483903 cites W2079349913 @default.
• W2007483903 cites W2091762501 @default.
• W2007483903 cites W2106137887 @default.
• W2007483903 cites W2106778550 @default.
• W2007483903 cites W2111158788 @default.
• W2007483903 cites W2238051651 @default.
• W2007483903 cites W2330762422 @default.
• W2007483903 cites W4241401982 @default.
• W2007483903 doi "https://doi.org/10.1016/j.humpath.2011.02.004" @default.
• W2007483903 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21663937" @default.
• W2007483903 hasPublicationYear "2011" @default.
• W2007483903 type Work @default.
• W2007483903 sameAs 2007483903 @default.
• W2007483903 citedByCount "123" @default.
• W2007483903 countsByYear W20074839032012 @default.
• W2007483903 countsByYear W20074839032013 @default.
• W2007483903 countsByYear W20074839032014 @default.
• W2007483903 countsByYear W20074839032015 @default.
• W2007483903 countsByYear W20074839032016 @default.
• W2007483903 countsByYear W20074839032017 @default.
• W2007483903 countsByYear W20074839032018 @default.
• W2007483903 countsByYear W20074839032019 @default.
• W2007483903 countsByYear W20074839032020 @default.
• W2007483903 countsByYear W20074839032021 @default.
• W2007483903 countsByYear W20074839032022 @default.
• W2007483903 countsByYear W20074839032023 @default.
• W2007483903 crossrefType "journal-article" @default.
• W2007483903 hasAuthorship W2007483903A5009195048 @default.
• W2007483903 hasAuthorship W2007483903A5021281217 @default.
• W2007483903 hasAuthorship W2007483903A5071072947 @default.
• W2007483903 hasConcept C104317684 @default.
• W2007483903 hasConcept C121608353 @default.
• W2007483903 hasConcept C124224327 @default.
• W2007483903 hasConcept C126322002 @default.
• W2007483903 hasConcept C142724271 @default.
• W2007483903 hasConcept C204232928 @default.
• W2007483903 hasConcept C2776530083 @default.
• W2007483903 hasConcept C2776833033 @default.
• W2007483903 hasConcept C2777546739 @default.
• W2007483903 hasConcept C2778057883 @default.
• W2007483903 hasConcept C2778981773 @default.
• W2007483903 hasConcept C2993294228 @default.
• W2007483903 hasConcept C4224716 @default.
• W2007483903 hasConcept C526584372 @default.
• W2007483903 hasConcept C55493867 @default.
• W2007483903 hasConcept C71924100 @default.
• W2007483903 hasConcept C86339819 @default.
• W2007483903 hasConcept C86803240 @default.
• W2007483903 hasConceptScore W2007483903C104317684 @default.
• W2007483903 hasConceptScore W2007483903C121608353 @default.
• W2007483903 hasConceptScore W2007483903C124224327 @default.
• W2007483903 hasConceptScore W2007483903C126322002 @default.
• W2007483903 hasConceptScore W2007483903C142724271 @default.
• W2007483903 hasConceptScore W2007483903C204232928 @default.
• W2007483903 hasConceptScore W2007483903C2776530083 @default.
• W2007483903 hasConceptScore W2007483903C2776833033 @default.
• W2007483903 hasConceptScore W2007483903C2777546739 @default.
• W2007483903 hasConceptScore W2007483903C2778057883 @default.
• W2007483903 hasConceptScore W2007483903C2778981773 @default.
• W2007483903 hasConceptScore W2007483903C2993294228 @default.
• W2007483903 hasConceptScore W2007483903C4224716 @default.
• W2007483903 hasConceptScore W2007483903C526584372 @default.
• W2007483903 hasConceptScore W2007483903C55493867 @default.
• W2007483903 hasConceptScore W2007483903C71924100 @default.
• W2007483903 hasConceptScore W2007483903C86339819 @default.
• W2007483903 hasConceptScore W2007483903C86803240 @default.
• W2007483903 hasIssue "12" @default.
• W2007483903 hasLocation W20074839031 @default.
• W2007483903 hasLocation W20074839032 @default.
• W2007483903 hasOpenAccess W2007483903 @default.
• W2007483903 hasPrimaryLocation W20074839031 @default.
• W2007483903 hasRelatedWork W1505942271 @default.
• W2007483903 hasRelatedWork W1964465819 @default.
• W2007483903 hasRelatedWork W1977157996 @default.
• W2007483903 hasRelatedWork W2029010919 @default.
• W2007483903 hasRelatedWork W2080968920 @default.
• W2007483903 hasRelatedWork W2087916660 @default.
• W2007483903 hasRelatedWork W2098597135 @default.
• W2007483903 hasRelatedWork W2102021118 @default.

• next