FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007484590> ?p ?o ?g. }

• W2007484590 abstract "In progressive immunoglobulin A nephropathy (IgAN), intravenous immunoglobulin (IVIg) treatment has been used to delay disease progression, but the long-term efficacy is largely unknown. We report the clinical outcomes after IVIg therapy in six male patients with progressive IgAN [median glomerular filtration rate (GFR) 31 ml/min per 1.73 m(2)] followed for a median observation period of 8 years. In this single-arm, non-randomized study, IVIg was given monthly at a dose of 2 g/kg body weight for 6 months. The course of renal function was assessed by linear regression analysis of GFR and proteinuria, and was compared to eight patients with IgAN (median GFR 29 ml/min per 1.73 m(2)) without IVIg as a contemporaneous control group. IgAN disease progression was delayed after IVIg therapy on average for 3 years. The mean loss of renal function decreased from -1.05 ml/min per month to -0.15 ml/min per month (P = 0.024) and proteinuria decreased from 2.4 g/l to 1.0 g/l (P = 0.015). The primary end-point (GFR < 10 ml/min or relapse) occurred 5.2 years (median; range 0.4-8.8) after the first IVIg pulse, and after 1.3 years (median; range 0.8-2.4) in the control group (P = 0.043). In Kaplan-Meier analysis, the median renal survival time with IVIg was prolonged by 3.5 years (IVIg 4.7 years versus control 1.2 years; P = 0.006). IVIg pulse therapy may be considered as a treatment option to reduce the loss of renal function and improve proteinuria in patients with progressive IgAN." @default.
• W2007484590 created "2016-06-24" @default.
• W2007484590 creator A5006607584 @default.
• W2007484590 creator A5015606205 @default.
• W2007484590 creator A5036440219 @default.
• W2007484590 creator A5055971502 @default.
• W2007484590 creator A5057985257 @default.
• W2007484590 creator A5062580306 @default.
• W2007484590 creator A5071120282 @default.
• W2007484590 creator A5087571933 @default.
• W2007484590 date "2006-10-01" @default.
• W2007484590 modified "2023-09-27" @default.
• W2007484590 title "High-dose intravenous immunoglobulin pulse therapy in patients with progressive immunoglobulin A nephropathy: a long-term follow-up" @default.
• W2007484590 cites W151431098 @default.
• W2007484590 cites W1549091490 @default.
• W2007484590 cites W1982085852 @default.
• W2007484590 cites W1989492092 @default.
• W2007484590 cites W1991027093 @default.
• W2007484590 cites W2031807034 @default.
• W2007484590 cites W2044890296 @default.
• W2007484590 cites W2090438027 @default.
• W2007484590 cites W2100253592 @default.
• W2007484590 cites W2105803357 @default.
• W2007484590 cites W2116730178 @default.
• W2007484590 cites W2118289765 @default.
• W2007484590 cites W2120038340 @default.
• W2007484590 cites W2125136564 @default.
• W2007484590 cites W2125558501 @default.
• W2007484590 cites W2125785855 @default.
• W2007484590 cites W2138668353 @default.
• W2007484590 cites W2139030893 @default.
• W2007484590 cites W2140445493 @default.
• W2007484590 cites W2140702251 @default.
• W2007484590 cites W2145936854 @default.
• W2007484590 cites W2157306342 @default.
• W2007484590 cites W2163889767 @default.
• W2007484590 cites W2168871627 @default.
• W2007484590 cites W2345529911 @default.
• W2007484590 cites W2408087895 @default.
• W2007484590 cites W2616639792 @default.
• W2007484590 cites W4239867451 @default.
• W2007484590 cites W48565388 @default.
• W2007484590 doi "https://doi.org/10.1111/j.1365-2249.2006.03189.x" @default.
• W2007484590 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1809721" @default.
• W2007484590 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16968397" @default.
• W2007484590 hasPublicationYear "2006" @default.
• W2007484590 type Work @default.
• W2007484590 sameAs 2007484590 @default.
• W2007484590 citedByCount "11" @default.
• W2007484590 countsByYear W20074845902015 @default.
• W2007484590 countsByYear W20074845902016 @default.
• W2007484590 countsByYear W20074845902017 @default.
• W2007484590 crossrefType "journal-article" @default.
• W2007484590 hasAuthorship W2007484590A5006607584 @default.
• W2007484590 hasAuthorship W2007484590A5015606205 @default.
• W2007484590 hasAuthorship W2007484590A5036440219 @default.
• W2007484590 hasAuthorship W2007484590A5055971502 @default.
• W2007484590 hasAuthorship W2007484590A5057985257 @default.
• W2007484590 hasAuthorship W2007484590A5062580306 @default.
• W2007484590 hasAuthorship W2007484590A5071120282 @default.
• W2007484590 hasAuthorship W2007484590A5087571933 @default.
• W2007484590 hasBestOaLocation W20074845902 @default.
• W2007484590 hasConcept C126322002 @default.
• W2007484590 hasConcept C126894567 @default.
• W2007484590 hasConcept C134018914 @default.
• W2007484590 hasConcept C159641895 @default.
• W2007484590 hasConcept C159654299 @default.
• W2007484590 hasConcept C203014093 @default.
• W2007484590 hasConcept C2779561371 @default.
• W2007484590 hasConcept C2780091579 @default.
• W2007484590 hasConcept C2781184683 @default.
• W2007484590 hasConcept C2909916134 @default.
• W2007484590 hasConcept C555293320 @default.
• W2007484590 hasConcept C71924100 @default.
• W2007484590 hasConcept C90924648 @default.
• W2007484590 hasConceptScore W2007484590C126322002 @default.
• W2007484590 hasConceptScore W2007484590C126894567 @default.
• W2007484590 hasConceptScore W2007484590C134018914 @default.
• W2007484590 hasConceptScore W2007484590C159641895 @default.
• W2007484590 hasConceptScore W2007484590C159654299 @default.
• W2007484590 hasConceptScore W2007484590C203014093 @default.
• W2007484590 hasConceptScore W2007484590C2779561371 @default.
• W2007484590 hasConceptScore W2007484590C2780091579 @default.
• W2007484590 hasConceptScore W2007484590C2781184683 @default.
• W2007484590 hasConceptScore W2007484590C2909916134 @default.
• W2007484590 hasConceptScore W2007484590C555293320 @default.
• W2007484590 hasConceptScore W2007484590C71924100 @default.
• W2007484590 hasConceptScore W2007484590C90924648 @default.
• W2007484590 hasLocation W20074845901 @default.
• W2007484590 hasLocation W20074845902 @default.
• W2007484590 hasLocation W20074845903 @default.
• W2007484590 hasOpenAccess W2007484590 @default.
• W2007484590 hasPrimaryLocation W20074845901 @default.
• W2007484590 hasRelatedWork W1536513376 @default.
• W2007484590 hasRelatedWork W2013701055 @default.
• W2007484590 hasRelatedWork W2062966026 @default.
• W2007484590 hasRelatedWork W2139990347 @default.
• W2007484590 hasRelatedWork W2238633398 @default.
• W2007484590 hasRelatedWork W2391246432 @default.
• W2007484590 hasRelatedWork W2401652391 @default.

• next