Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007495537> ?p ?o ?g. }
- W2007495537 endingPage "2826" @default.
- W2007495537 startingPage "2817" @default.
- W2007495537 abstract "A series of 1-(substituted benzylidene/ethylidene)-4-(naphthalen-1-yl)semicarbazides (3a–19a; 3b–6b) were synthesized in good yield and evaluated for their anticonvulsant and antioxidant activities. The structures of the synthesized compounds were confirmed on the basis of their spectral data and elemental analysis. All of the compounds were found to be active in MES and scPTZ tests. Quantum chemical studies were carried out on these compounds to understand the structural features essential for activity. Electronic properties were found to be the principal modulator of both anticonvulsant and antioxidant activities. A computational study was carried out for prediction of pharmacokinetic properties and none of the compounds violated Lipinski’s rule of 5, making them potentially promising agents for the treatment of epilepsy." @default.
- W2007495537 created "2016-06-24" @default.
- W2007495537 creator A5001549657 @default.
- W2007495537 creator A5012632134 @default.
- W2007495537 creator A5036116066 @default.
- W2007495537 date "2010-07-01" @default.
- W2007495537 modified "2023-09-25" @default.
- W2007495537 title "Combating oxidative stress in epilepsy: Design, synthesis, quantum chemical studies and anticonvulsant evaluation of 1-(substituted benzylidene/ethylidene)-4-(naphthalen-1-yl)semicarbazides" @default.
- W2007495537 cites W1547367931 @default.
- W2007495537 cites W1775749144 @default.
- W2007495537 cites W1844162254 @default.
- W2007495537 cites W191227402 @default.
- W2007495537 cites W1964235811 @default.
- W2007495537 cites W1971843669 @default.
- W2007495537 cites W1972122552 @default.
- W2007495537 cites W1975368607 @default.
- W2007495537 cites W1983310681 @default.
- W2007495537 cites W1983934875 @default.
- W2007495537 cites W1988536360 @default.
- W2007495537 cites W1995331974 @default.
- W2007495537 cites W1995386153 @default.
- W2007495537 cites W2004792176 @default.
- W2007495537 cites W2004880366 @default.
- W2007495537 cites W2005457679 @default.
- W2007495537 cites W2007993900 @default.
- W2007495537 cites W2009268204 @default.
- W2007495537 cites W2012925503 @default.
- W2007495537 cites W2019306848 @default.
- W2007495537 cites W2031044425 @default.
- W2007495537 cites W2033495141 @default.
- W2007495537 cites W2037025679 @default.
- W2007495537 cites W2043374469 @default.
- W2007495537 cites W2047562247 @default.
- W2007495537 cites W2050736164 @default.
- W2007495537 cites W2054888659 @default.
- W2007495537 cites W2055305894 @default.
- W2007495537 cites W2058933166 @default.
- W2007495537 cites W2060445540 @default.
- W2007495537 cites W2063576996 @default.
- W2007495537 cites W2065947654 @default.
- W2007495537 cites W2066785015 @default.
- W2007495537 cites W2072075804 @default.
- W2007495537 cites W2072830142 @default.
- W2007495537 cites W2075308518 @default.
- W2007495537 cites W2076710249 @default.
- W2007495537 cites W2078641102 @default.
- W2007495537 cites W2080644246 @default.
- W2007495537 cites W2088105132 @default.
- W2007495537 cites W2088620464 @default.
- W2007495537 cites W2091110063 @default.
- W2007495537 cites W2095274949 @default.
- W2007495537 cites W2124603205 @default.
- W2007495537 cites W2126679408 @default.
- W2007495537 cites W2127336290 @default.
- W2007495537 cites W2135732933 @default.
- W2007495537 cites W2148271626 @default.
- W2007495537 cites W2150562758 @default.
- W2007495537 cites W2155358697 @default.
- W2007495537 cites W2155633484 @default.
- W2007495537 cites W2159305277 @default.
- W2007495537 cites W2159340054 @default.
- W2007495537 cites W2168174626 @default.
- W2007495537 cites W2171448878 @default.
- W2007495537 cites W2323471917 @default.
- W2007495537 cites W2949447975 @default.
- W2007495537 cites W2950697616 @default.
- W2007495537 doi "https://doi.org/10.1016/j.ejmech.2010.02.063" @default.
- W2007495537 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20356656" @default.
- W2007495537 hasPublicationYear "2010" @default.
- W2007495537 type Work @default.
- W2007495537 sameAs 2007495537 @default.
- W2007495537 citedByCount "29" @default.
- W2007495537 countsByYear W20074955372012 @default.
- W2007495537 countsByYear W20074955372013 @default.
- W2007495537 countsByYear W20074955372014 @default.
- W2007495537 countsByYear W20074955372015 @default.
- W2007495537 countsByYear W20074955372016 @default.
- W2007495537 countsByYear W20074955372017 @default.
- W2007495537 countsByYear W20074955372018 @default.
- W2007495537 countsByYear W20074955372019 @default.
- W2007495537 countsByYear W20074955372020 @default.
- W2007495537 countsByYear W20074955372022 @default.
- W2007495537 crossrefType "journal-article" @default.
- W2007495537 hasAuthorship W2007495537A5001549657 @default.
- W2007495537 hasAuthorship W2007495537A5012632134 @default.
- W2007495537 hasAuthorship W2007495537A5036116066 @default.
- W2007495537 hasConcept C147597530 @default.
- W2007495537 hasConcept C169760540 @default.
- W2007495537 hasConcept C178790620 @default.
- W2007495537 hasConcept C185592680 @default.
- W2007495537 hasConcept C21951064 @default.
- W2007495537 hasConcept C2775858608 @default.
- W2007495537 hasConcept C2776151105 @default.
- W2007495537 hasConcept C2778004101 @default.
- W2007495537 hasConcept C2778186239 @default.
- W2007495537 hasConcept C2991951333 @default.
- W2007495537 hasConcept C32909587 @default.
- W2007495537 hasConcept C55493867 @default.