Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007497470> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2007497470 endingPage "352" @default.
- W2007497470 startingPage "341" @default.
- W2007497470 abstract "An extremely sensitive and reliable bioassay for inhibin based on inhibition of ovine pituitary FSH secretion in vitro was developed and used to measure exogenous and endogenous inhibin activity in the ewe. The sheep inhibin bioassay is 30- to 40-fold more sensitive than conventional rat inhibin bioassays. The minimum sensitivity of each bioassay in the measurement of inhibin activity in 1 ml of sheep serum is 220 mu. and 4080 mu. in the sheep and rat bioassays respectively. This sensitive inhibin bioassay has permitted, for the first time, the measurement of endogenous inhibin in the peripheral and ovarian vein blood of the sheep, as well as exogenously administered inhibin. The half-life of exogenously administered ovine inhibin (in follicular fluid) in the sheep was calculated as two components (18-24 and 50-60 min) from the inhibin profiles of six ewes. Inhibin contained in the ovine follicular fluid, given as a bolus i.v. injection, increased to maximum levels after 5 min and then remained increased for 10-32 min depending upon the dose administered, before exponentially decaying. The time for inhibin to exert its effect ranged from 3 to 6 h after injection and appeared to be dose-related. The bolus injection of inhibin, apart from causing suppression of FSH, evoked a large rebound increase of FSH up to 400% of preinjection levels. The development of the sheep bioassay will allow the measurement of biologically active inhibin in the peripheral circulation and ovarian vein blood of sheep with the possibility of extending this to man." @default.
- W2007497470 created "2016-06-24" @default.
- W2007497470 creator A5022230895 @default.
- W2007497470 creator A5039781020 @default.
- W2007497470 creator A5058920267 @default.
- W2007497470 date "1986-08-01" @default.
- W2007497470 modified "2023-09-27" @default.
- W2007497470 title "Measurement of exogenous and endogenous inhibin in sheep serum using a new and extremely sensitive bioassay for inhibin based on inhibition of ovine pituitary FSH secretion in vitro" @default.
- W2007497470 doi "https://doi.org/10.1677/joe.0.1100341" @default.
- W2007497470 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3091750" @default.
- W2007497470 hasPublicationYear "1986" @default.
- W2007497470 type Work @default.
- W2007497470 sameAs 2007497470 @default.
- W2007497470 citedByCount "83" @default.
- W2007497470 countsByYear W20074974702012 @default.
- W2007497470 countsByYear W20074974702016 @default.
- W2007497470 countsByYear W20074974702020 @default.
- W2007497470 crossrefType "journal-article" @default.
- W2007497470 hasAuthorship W2007497470A5022230895 @default.
- W2007497470 hasAuthorship W2007497470A5039781020 @default.
- W2007497470 hasAuthorship W2007497470A5058920267 @default.
- W2007497470 hasConcept C104488531 @default.
- W2007497470 hasConcept C116073593 @default.
- W2007497470 hasConcept C126322002 @default.
- W2007497470 hasConcept C134018914 @default.
- W2007497470 hasConcept C16613235 @default.
- W2007497470 hasConcept C187785154 @default.
- W2007497470 hasConcept C196843134 @default.
- W2007497470 hasConcept C202751555 @default.
- W2007497470 hasConcept C2776188440 @default.
- W2007497470 hasConcept C2776690073 @default.
- W2007497470 hasConcept C2777658017 @default.
- W2007497470 hasConcept C43376680 @default.
- W2007497470 hasConcept C54355233 @default.
- W2007497470 hasConcept C55493867 @default.
- W2007497470 hasConcept C71315377 @default.
- W2007497470 hasConcept C71924100 @default.
- W2007497470 hasConcept C86803240 @default.
- W2007497470 hasConcept C95444343 @default.
- W2007497470 hasConceptScore W2007497470C104488531 @default.
- W2007497470 hasConceptScore W2007497470C116073593 @default.
- W2007497470 hasConceptScore W2007497470C126322002 @default.
- W2007497470 hasConceptScore W2007497470C134018914 @default.
- W2007497470 hasConceptScore W2007497470C16613235 @default.
- W2007497470 hasConceptScore W2007497470C187785154 @default.
- W2007497470 hasConceptScore W2007497470C196843134 @default.
- W2007497470 hasConceptScore W2007497470C202751555 @default.
- W2007497470 hasConceptScore W2007497470C2776188440 @default.
- W2007497470 hasConceptScore W2007497470C2776690073 @default.
- W2007497470 hasConceptScore W2007497470C2777658017 @default.
- W2007497470 hasConceptScore W2007497470C43376680 @default.
- W2007497470 hasConceptScore W2007497470C54355233 @default.
- W2007497470 hasConceptScore W2007497470C55493867 @default.
- W2007497470 hasConceptScore W2007497470C71315377 @default.
- W2007497470 hasConceptScore W2007497470C71924100 @default.
- W2007497470 hasConceptScore W2007497470C86803240 @default.
- W2007497470 hasConceptScore W2007497470C95444343 @default.
- W2007497470 hasIssue "2" @default.
- W2007497470 hasLocation W20074974701 @default.
- W2007497470 hasLocation W20074974702 @default.
- W2007497470 hasOpenAccess W2007497470 @default.
- W2007497470 hasPrimaryLocation W20074974701 @default.
- W2007497470 hasRelatedWork W1970739379 @default.
- W2007497470 hasRelatedWork W2007497470 @default.
- W2007497470 hasRelatedWork W2015874753 @default.
- W2007497470 hasRelatedWork W2027748287 @default.
- W2007497470 hasRelatedWork W2027938488 @default.
- W2007497470 hasRelatedWork W2043899786 @default.
- W2007497470 hasRelatedWork W2086825515 @default.
- W2007497470 hasRelatedWork W2153915731 @default.
- W2007497470 hasRelatedWork W2164661085 @default.
- W2007497470 hasRelatedWork W2465396404 @default.
- W2007497470 hasVolume "110" @default.
- W2007497470 isParatext "false" @default.
- W2007497470 isRetracted "false" @default.
- W2007497470 magId "2007497470" @default.
- W2007497470 workType "article" @default.