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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007517588> ?p ?o ?g. }

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• W2007517588 abstract "Arg-vasopressin (AVP) stimulates the production of inositol-1,4,5-trisphosphate, inositol-1,4-bisphosphate and inositol-1-phosphate in A10 smooth muscle cell line. The AVP stimulation is rapid, time and dose dependent with an ED 50 value of 5 nM. Protein kinase C activator, phorbol ester blocks the AVP effect on the production of inositol phosphates, suggesting that AVP induced phospholipase C (PLC) activation is under the negative feedback regulation by diacylglycerol production. Prolonged overnight treatment with either pertussis toxin and cholera toxin resulted partial inhibition of AVP-induced production of inositol phosphates. This result suggests that a noval G-protein similar to transducin might be involved in the AVP-induced PLC activation." @default.
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• W2007517588 date "1987-07-01" @default.
• W2007517588 modified "2023-09-26" @default.
• W2007517588 title "A pertussis/cholera toxin sensitive G-protein may mediate vasopressin-induced inositol phosphate formation in smooth muscle cell" @default.
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• W2007517588 doi "https://doi.org/10.1016/0006-291x(87)90615-2" @default.
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