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- W2007561525 abstract "Red palm oil (RPO) contains significant levels of carotenoids and Vitamin E. In this experiment we compared the inhibitory effects of RPO (7% and 14% levels) and soybean oil (7% and 14%) on azoxymethane (AOM) induced aberrant crypt foci (ACF). Thirty-two male Fisher 344 rats were randomly assigned to four groups. Two groups received AIN-93G control (C) diet containing 7% and 14% soybean oil (SBO), respectively. Groups 3 and 4 received a treatment diet consisting of 7% and 14% RPO, respectively. The rats received subcutaneous injections of AOM at 16 mg/kg body weight at 7 and 8 weeks of age. At 17 weeks of age rats were killed by CO2 asphyxiation. Numbers of ACF (mean ± SE) in the proximal and distal colon were: 39.9 ± 0.9, 53.8 ± 2.8, 26.0 ± 3.0, 27.5 ± 1.5 and 118.2 ± 1.7, 125.6 ± 3.2, 41 ± 7, 52.3 ± 1.8 in rats fed 7% SBO, 14% SBO, 7% RPO and 14% RPO, respectively. The results of this study showed that RPO reduced the incidence of AOM induced ACF and may therefore have a beneficial effect in reducing the incidence of colon cancer." @default.
- W2007561525 created "2016-06-24" @default.
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- W2007561525 date "2006-10-01" @default.
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- W2007561525 title "Red palm oil suppresses the formation of azoxymethane (AOM) induced aberrant crypt foci (ACF) in Fisher 344 male rats" @default.
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- W2007561525 doi "https://doi.org/10.1016/j.fct.2006.05.002" @default.
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