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- W2007603025 abstract "<h3>Objective</h3> To investigate occurrences of hearing loss and hearing complaints among patients with head and neck tumors who underwent radiotherapy. <h3>Design</h3> Prospective case-control study. <h3>Setting</h3> Tertiary care hospital. <h3>Participants</h3> Two hundred eighty-two participants underwent evaluation, including 141 with head and neck tumors and 141 as an age-matched control group. The controls had never undergone oncological treatment that put their hearing at risk. <h3>Main Outcome Measures</h3> Results of audiological evaluation, including the Hearing Handicap Inventory for the Elderly questionnaire and pure-tone, speech, and immittance audiometry, and radiation dose received by the auditory system (based on the percentage of the external auditory canal included in the radiation field). <h3>Results</h3> We observed occurrences of hearing loss in 102 (72.3%) of the participants exposed to radiotherapy and 69 (48.9%) of the control group (<i>P</i> < .001). Hearing losses were mostly sensorineural and of mild degree, but those exposed to radiotherapy more frequently presented with severe and mixed-type hearing losses (<i>P</i> < .001). Of the participants exposed to radiotherapy, 19.1% had a severe handicap (<i>P</i> < .001). <h3>Conclusion</h3> Patients undergoing radiotherapy in the head and neck region have a higher incidence of hearing loss and more severe hearing handicap. <h3>Trial Registration</h3> clinicaltrials.gov Identifier:NCT01102621" @default.
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- W2007603025 date "2010-11-15" @default.
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- W2007603025 title "Hearing Loss and Complaint in Patients With Head and Neck Cancer Treated With Radiotherapy" @default.
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- W2007603025 doi "https://doi.org/10.1001/archoto.2010.180" @default.
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