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- W2007606947 abstract "Summary Human cortical areas involved in pain modulation exert a causal influence upon areas activated by painful stimuli, which is stable over time and tasks. The human ‘pain network’ includes cortical areas that are activated during the response to painful stimuli (termed category 1) or during psychological processes that modulate pain, for example, distraction (termed category 2). These categories include parts of the parasylvian (PS), medial frontal (MF), and paracentral cortex (S1&M1). Here we test the hypothesis that causal interactions both within and between category 1 and category 2 modules occur during attention to a painful stimulus. Event-related causality (ERC) was calculated from local field potentials recorded directly from these cortical areas during the response to a painful cutaneous laser stimulus in patients being monitored for epilepsy. The number of electrodes involved in pairs with significant ERC in category 1 was greater for pre-stimulus vs post-stimulus and for attention vs distraction. This is consistent with our prior evidence that the category 1 ‘pain network’ changes rapidly with time intervals and tasks. In contrast, the interaction between categories was often unchanged or stable across intervals and tasks, particularly in MF. The proportion of contacts involved in interactions with PS was greater during distraction vs attention while activation was less, which suggests that distraction involves an inhibitory process in PS. Functional interactions between categories were overwhelmingly in the direction from category 2 > 1, particularly for contacts in MF which often had a driver role. These results demonstrate that MF is densely interconnected throughout the ‘pain network’ so that stimulation of MF might be used to disrupt the ‘pain network’ as a therapy for pain." @default.
- W2007606947 created "2016-06-24" @default.
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- W2007606947 date "2011-12-01" @default.
- W2007606947 modified "2023-09-27" @default.
- W2007606947 title "Attention to painful cutaneous laser stimuli evokes directed functional interactions between human sensory and modulatory pain-related cortical areas" @default.
- W2007606947 cites W1801800938 @default.
- W2007606947 cites W1802301839 @default.
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- W2007606947 cites W1958208694 @default.
- W2007606947 cites W1964609779 @default.
- W2007606947 cites W1964769652 @default.
- W2007606947 cites W1965571403 @default.
- W2007606947 cites W1971131101 @default.
- W2007606947 cites W1971218440 @default.
- W2007606947 cites W1971525352 @default.
- W2007606947 cites W1978998130 @default.
- W2007606947 cites W1980572378 @default.
- W2007606947 cites W1982113426 @default.
- W2007606947 cites W1983006199 @default.
- W2007606947 cites W1983523765 @default.
- W2007606947 cites W1989522832 @default.
- W2007606947 cites W1990767952 @default.
- W2007606947 cites W1997035108 @default.
- W2007606947 cites W1999335988 @default.
- W2007606947 cites W2000053985 @default.
- W2007606947 cites W2007791604 @default.
- W2007606947 cites W2009415578 @default.
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- W2007606947 cites W2016493469 @default.
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- W2007606947 cites W2018377505 @default.
- W2007606947 cites W2019021660 @default.
- W2007606947 cites W2025577666 @default.
- W2007606947 cites W2026896852 @default.
- W2007606947 cites W2028850601 @default.
- W2007606947 cites W2037230306 @default.
- W2007606947 cites W2043172641 @default.
- W2007606947 cites W2049955088 @default.
- W2007606947 cites W2051572527 @default.
- W2007606947 cites W2055720021 @default.
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- W2007606947 cites W2060012280 @default.
- W2007606947 cites W2065240872 @default.
- W2007606947 cites W2067585008 @default.
- W2007606947 cites W2068341702 @default.
- W2007606947 cites W2073512103 @default.
- W2007606947 cites W2074501647 @default.
- W2007606947 cites W2081326318 @default.
- W2007606947 cites W2082604976 @default.
- W2007606947 cites W2084737987 @default.
- W2007606947 cites W2085846591 @default.
- W2007606947 cites W2088992072 @default.
- W2007606947 cites W2095706095 @default.
- W2007606947 cites W2096575475 @default.
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- W2007606947 cites W2109401833 @default.
- W2007606947 cites W2121962606 @default.
- W2007606947 cites W2131165483 @default.
- W2007606947 cites W2135032219 @default.
- W2007606947 cites W2135487512 @default.
- W2007606947 cites W2142635246 @default.
- W2007606947 cites W2142759086 @default.
- W2007606947 cites W2150591570 @default.
- W2007606947 cites W2151651036 @default.
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- W2007606947 doi "https://doi.org/10.1016/j.pain.2011.09.002" @default.
- W2007606947 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3433227" @default.
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