Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007610462> ?p ?o ?g. }
- W2007610462 endingPage "50" @default.
- W2007610462 startingPage "37" @default.
- W2007610462 abstract "The simian immunodeficiency virus (SIV) capsid protein (CA), a constituent of the Pr55Gag polyprotein, is phosphorylated in virions but not in virus-producing cells (Rue, S.M., Roos, J.W., Tarwater, P.M., Clements, J.E., Barber, S.A., 2005. Phosphorylation and proteolytic cleavage of gag proteins in budded simian immunodeficiency virus. J. Virol. 79 (4), 2484-2492.). Using phosphoamino acid analysis of CA, we show that serine is the primary phosphate acceptor. A series of substitution mutants of serines in the CA domain of Pr55Gag were constructed in the infectious viral clone SIVmac239. These virus mutants were examined for defects in virus replication and virion infectivity, release, and morphology, as well as alterations in phosphorylation of CA-containing proteins. Although the virus mutants exhibited a number of replication defects, none of these defects could be directly attributed to aberrant CA phosphorylation. A novel defect was a block in early budding, which was common among several virus mutants with substitutions in the CA N terminus. Together, these results indicate that certain residues in the CA N terminus are crucial for early budding events." @default.
- W2007610462 created "2016-06-24" @default.
- W2007610462 creator A5007231913 @default.
- W2007610462 creator A5007392842 @default.
- W2007610462 creator A5036649833 @default.
- W2007610462 creator A5073149657 @default.
- W2007610462 date "2005-05-01" @default.
- W2007610462 modified "2023-09-26" @default.
- W2007610462 title "Conserved serines in simian immunodeficiency virus capsid are required for virus budding" @default.
- W2007610462 cites W1528478642 @default.
- W2007610462 cites W1576742764 @default.
- W2007610462 cites W1579191879 @default.
- W2007610462 cites W1585440676 @default.
- W2007610462 cites W1595806441 @default.
- W2007610462 cites W1599129674 @default.
- W2007610462 cites W1611298747 @default.
- W2007610462 cites W1777421142 @default.
- W2007610462 cites W1903380786 @default.
- W2007610462 cites W1905521254 @default.
- W2007610462 cites W1932084946 @default.
- W2007610462 cites W1968391451 @default.
- W2007610462 cites W1969392841 @default.
- W2007610462 cites W1970630169 @default.
- W2007610462 cites W1974224443 @default.
- W2007610462 cites W1979556823 @default.
- W2007610462 cites W1983553980 @default.
- W2007610462 cites W1987263968 @default.
- W2007610462 cites W1989884289 @default.
- W2007610462 cites W1993377322 @default.
- W2007610462 cites W2000734326 @default.
- W2007610462 cites W2009465113 @default.
- W2007610462 cites W2013652077 @default.
- W2007610462 cites W2013653455 @default.
- W2007610462 cites W2013908252 @default.
- W2007610462 cites W2015090760 @default.
- W2007610462 cites W2020752706 @default.
- W2007610462 cites W2028156315 @default.
- W2007610462 cites W2045185169 @default.
- W2007610462 cites W2053512389 @default.
- W2007610462 cites W2056548409 @default.
- W2007610462 cites W2059841928 @default.
- W2007610462 cites W2059910556 @default.
- W2007610462 cites W2060952336 @default.
- W2007610462 cites W2066053818 @default.
- W2007610462 cites W2068500252 @default.
- W2007610462 cites W2076877843 @default.
- W2007610462 cites W2078594804 @default.
- W2007610462 cites W2084607977 @default.
- W2007610462 cites W2098158896 @default.
- W2007610462 cites W2108612435 @default.
- W2007610462 cites W2121753315 @default.
- W2007610462 cites W2129204559 @default.
- W2007610462 cites W2137919235 @default.
- W2007610462 cites W2138263779 @default.
- W2007610462 cites W2141772131 @default.
- W2007610462 cites W2145040935 @default.
- W2007610462 cites W2150656125 @default.
- W2007610462 cites W2151116772 @default.
- W2007610462 cites W2157055613 @default.
- W2007610462 cites W2157103983 @default.
- W2007610462 cites W2159504933 @default.
- W2007610462 cites W2161909898 @default.
- W2007610462 cites W2248336029 @default.
- W2007610462 cites W4233721986 @default.
- W2007610462 cites W4299506417 @default.
- W2007610462 cites W2168208896 @default.
- W2007610462 doi "https://doi.org/10.1016/j.virol.2005.03.006" @default.
- W2007610462 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15866069" @default.
- W2007610462 hasPublicationYear "2005" @default.
- W2007610462 type Work @default.
- W2007610462 sameAs 2007610462 @default.
- W2007610462 citedByCount "1" @default.
- W2007610462 crossrefType "journal-article" @default.
- W2007610462 hasAuthorship W2007610462A5007231913 @default.
- W2007610462 hasAuthorship W2007610462A5007392842 @default.
- W2007610462 hasAuthorship W2007610462A5036649833 @default.
- W2007610462 hasAuthorship W2007610462A5073149657 @default.
- W2007610462 hasBestOaLocation W20076104621 @default.
- W2007610462 hasConcept C104317684 @default.
- W2007610462 hasConcept C106358424 @default.
- W2007610462 hasConcept C11960822 @default.
- W2007610462 hasConcept C140704245 @default.
- W2007610462 hasConcept C143065580 @default.
- W2007610462 hasConcept C153911025 @default.
- W2007610462 hasConcept C159047783 @default.
- W2007610462 hasConcept C198410946 @default.
- W2007610462 hasConcept C202878990 @default.
- W2007610462 hasConcept C2522874641 @default.
- W2007610462 hasConcept C2777995582 @default.
- W2007610462 hasConcept C54355233 @default.
- W2007610462 hasConcept C6881719 @default.
- W2007610462 hasConcept C86295872 @default.
- W2007610462 hasConcept C86803240 @default.
- W2007610462 hasConcept C95444343 @default.
- W2007610462 hasConceptScore W2007610462C104317684 @default.
- W2007610462 hasConceptScore W2007610462C106358424 @default.
- W2007610462 hasConceptScore W2007610462C11960822 @default.
- W2007610462 hasConceptScore W2007610462C140704245 @default.