FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007643532> ?p ?o ?g. }

• W2007643532 endingPage "7511" @default.
• W2007643532 startingPage "7500" @default.
• W2007643532 abstract "ABSTRACT The envelope is an essential structure of the bacterial cell, and maintaining its integrity is a prerequisite for survival. To ensure proper function, transmembrane signal-transducing systems, such as two-component systems (TCS) and extracytoplasmic function (ECF) σ factors, closely monitor its condition and respond to harmful perturbations. Both systems consist of a transmembrane sensor protein (histidine kinase or anti-σ factor, respectively) and a corresponding cytoplasmic transcriptional regulator (response regulator or σ factor, respectively) that mediates the cellular response through differential gene expression. The regulatory network of the cell envelope stress response is well studied in the gram-positive model organism Bacillus subtilis . It consists of at least two ECF σ factors and four two-component systems. In this study, we describe the corresponding network in a close relative, Bacillus licheniformis . Based on sequence homology, domain architecture, and genomic context, we identified five TCS and eight ECF σ factors as potential candidate regulatory systems mediating cell envelope stress response in this organism. We characterized the corresponding regulatory network by comparative transcriptomics and regulon mining as an initial screening tool. Subsequent in-depth transcriptional profiling was applied to define the inducer specificity of each identified cell envelope stress sensor. A total of three TCS and seven ECF σ factors were shown to be induced by cell envelope stress in B. licheniformis. We noted a number of significant differences, indicative of a regulatory divergence between the two Bacillus species, in addition to the expected overlap in the respective responses." @default.
• W2007643532 created "2016-06-24" @default.
• W2007643532 creator A5011847447 @default.
• W2007643532 creator A5037763495 @default.
• W2007643532 creator A5053659069 @default.
• W2007643532 creator A5057862815 @default.
• W2007643532 date "2006-11-01" @default.
• W2007643532 modified "2023-10-17" @default.
• W2007643532 title "Cell Envelope Stress Response in <i>Bacillus licheniformis</i> : Integrating Comparative Genomics, Transcriptional Profiling, and Regulon Mining To Decipher a Complex Regulatory Network" @default.
• W2007643532 cites W1498884303 @default.
• W2007643532 cites W1499519022 @default.
• W2007643532 cites W1505235074 @default.
• W2007643532 cites W1530956256 @default.
• W2007643532 cites W1557538185 @default.
• W2007643532 cites W1701180156 @default.
• W2007643532 cites W1751061835 @default.
• W2007643532 cites W1863386058 @default.
• W2007643532 cites W1909878702 @default.
• W2007643532 cites W1977922844 @default.
• W2007643532 cites W1979696568 @default.
• W2007643532 cites W1985000897 @default.
• W2007643532 cites W1989823376 @default.
• W2007643532 cites W1991303432 @default.
• W2007643532 cites W1993163345 @default.
• W2007643532 cites W2005489232 @default.
• W2007643532 cites W2014275320 @default.
• W2007643532 cites W2017212227 @default.
• W2007643532 cites W2019623096 @default.
• W2007643532 cites W2022926885 @default.
• W2007643532 cites W2024675792 @default.
• W2007643532 cites W2029480898 @default.
• W2007643532 cites W2040439830 @default.
• W2007643532 cites W2041025550 @default.
• W2007643532 cites W2043134034 @default.
• W2007643532 cites W2044521292 @default.
• W2007643532 cites W2046767419 @default.
• W2007643532 cites W2051049929 @default.
• W2007643532 cites W2055016234 @default.
• W2007643532 cites W2068166540 @default.
• W2007643532 cites W2087823469 @default.
• W2007643532 cites W2091160279 @default.
• W2007643532 cites W2099216699 @default.
• W2007643532 cites W2105222452 @default.
• W2007643532 cites W2106353887 @default.
• W2007643532 cites W2107779380 @default.
• W2007643532 cites W2107824577 @default.
• W2007643532 cites W2111993374 @default.
• W2007643532 cites W2113230913 @default.
• W2007643532 cites W2113247851 @default.
• W2007643532 cites W2114878533 @default.
• W2007643532 cites W2115317294 @default.
• W2007643532 cites W2115490768 @default.
• W2007643532 cites W2116810280 @default.
• W2007643532 cites W2118204420 @default.
• W2007643532 cites W2123150370 @default.
• W2007643532 cites W2127597865 @default.
• W2007643532 cites W2127747618 @default.
• W2007643532 cites W2131709544 @default.
• W2007643532 cites W2138307025 @default.
• W2007643532 cites W2146731040 @default.
• W2007643532 cites W2151693231 @default.
• W2007643532 cites W2152770371 @default.
• W2007643532 cites W2156266252 @default.
• W2007643532 cites W2160113173 @default.
• W2007643532 cites W2164544041 @default.
• W2007643532 cites W2165191229 @default.
• W2007643532 cites W2165407281 @default.
• W2007643532 cites W2168521266 @default.
• W2007643532 cites W4295992544 @default.
• W2007643532 doi "https://doi.org/10.1128/jb.01110-06" @default.
• W2007643532 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1636251" @default.
• W2007643532 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16936031" @default.
• W2007643532 hasPublicationYear "2006" @default.
• W2007643532 type Work @default.
• W2007643532 sameAs 2007643532 @default.
• W2007643532 citedByCount "37" @default.
• W2007643532 countsByYear W20076435322012 @default.
• W2007643532 countsByYear W20076435322013 @default.
• W2007643532 countsByYear W20076435322016 @default.
• W2007643532 countsByYear W20076435322019 @default.
• W2007643532 countsByYear W20076435322020 @default.
• W2007643532 countsByYear W20076435322021 @default.
• W2007643532 countsByYear W20076435322022 @default.
• W2007643532 countsByYear W20076435322023 @default.
• W2007643532 crossrefType "journal-article" @default.
• W2007643532 hasAuthorship W2007643532A5011847447 @default.
• W2007643532 hasAuthorship W2007643532A5037763495 @default.
• W2007643532 hasAuthorship W2007643532A5053659069 @default.
• W2007643532 hasAuthorship W2007643532A5057862815 @default.
• W2007643532 hasBestOaLocation W20076435322 @default.
• W2007643532 hasConcept C104317684 @default.
• W2007643532 hasConcept C143065580 @default.
• W2007643532 hasConcept C150194340 @default.
• W2007643532 hasConcept C165864922 @default.
• W2007643532 hasConcept C27153228 @default.
• W2007643532 hasConcept C2776527165 @default.
• W2007643532 hasConcept C2777272437 @default.
• W2007643532 hasConcept C2781196521 @default.

• next