Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007646238> ?p ?o ?g. }
- W2007646238 endingPage "6" @default.
- W2007646238 startingPage "1" @default.
- W2007646238 abstract "Primary Biliary Cirrhosis (PBC) is considered an autoimmune disease characterized by immune-mediated destruction of the intrahepatic bile ducts and its characteristic serologic marker, the anti-mitochondrial antibody (AMA). Several factors were proposed to clarify the pathological and immunological mechanisms of PBC. Immunological reaction with a bacterial or a viral association was identified in the previous report, and it seems probable that PBC was thought to have such an etiology. The majority of patients with PBC was reported to have both RT-PCR and immunohistochemistry evidence of human betaretrovirus infection in lymph nodes or in 2008, the patient who developed PBC with high HIV viral load had an antiviral therapy and recovered. To understand the etiology of PBC associated with infection, several factors should be considered and especially animal models may be useful. In this paper, we introduce three typical animal models of PBC: the dominant-negative form of transforming growth factor- β receptor type II (dnTGF β RII) mouse, IL-2R α −/− mouse and NOD.c3c4 mouse, are enumerated and described, and we discuss previous reports of viral infection associated with PBC and consider the etiology of PBC from our analysis of results in NOD.c3c4 mouse." @default.
- W2007646238 created "2016-06-24" @default.
- W2007646238 creator A5029930183 @default.
- W2007646238 creator A5047380294 @default.
- W2007646238 creator A5066151943 @default.
- W2007646238 date "2012-01-01" @default.
- W2007646238 modified "2023-09-23" @default.
- W2007646238 title "PBC: Animal Models of Cholangiopathies and Possible Endogenous Viral Infections" @default.
- W2007646238 cites W1480189234 @default.
- W2007646238 cites W1503866127 @default.
- W2007646238 cites W1526505522 @default.
- W2007646238 cites W1650215555 @default.
- W2007646238 cites W1956131600 @default.
- W2007646238 cites W1971693959 @default.
- W2007646238 cites W1974359849 @default.
- W2007646238 cites W1977351761 @default.
- W2007646238 cites W1977492688 @default.
- W2007646238 cites W1981874823 @default.
- W2007646238 cites W1982865990 @default.
- W2007646238 cites W1986800829 @default.
- W2007646238 cites W1987824891 @default.
- W2007646238 cites W1996378263 @default.
- W2007646238 cites W2004708295 @default.
- W2007646238 cites W2004944019 @default.
- W2007646238 cites W2008779414 @default.
- W2007646238 cites W2010073113 @default.
- W2007646238 cites W2014102565 @default.
- W2007646238 cites W2031205383 @default.
- W2007646238 cites W2031252695 @default.
- W2007646238 cites W2033411989 @default.
- W2007646238 cites W2039347592 @default.
- W2007646238 cites W2041466047 @default.
- W2007646238 cites W2044119777 @default.
- W2007646238 cites W2045454487 @default.
- W2007646238 cites W2053482393 @default.
- W2007646238 cites W2055752453 @default.
- W2007646238 cites W2060817012 @default.
- W2007646238 cites W2074202083 @default.
- W2007646238 cites W2078610347 @default.
- W2007646238 cites W2080938189 @default.
- W2007646238 cites W2083311645 @default.
- W2007646238 cites W2087646912 @default.
- W2007646238 cites W2093304786 @default.
- W2007646238 cites W2096139310 @default.
- W2007646238 cites W2100632875 @default.
- W2007646238 cites W2103031848 @default.
- W2007646238 cites W2103656186 @default.
- W2007646238 cites W2112332162 @default.
- W2007646238 cites W2119731667 @default.
- W2007646238 cites W2119812397 @default.
- W2007646238 cites W2134516820 @default.
- W2007646238 cites W2138314644 @default.
- W2007646238 cites W2145991280 @default.
- W2007646238 cites W2147507929 @default.
- W2007646238 cites W2155524887 @default.
- W2007646238 cites W2160005035 @default.
- W2007646238 cites W2162354645 @default.
- W2007646238 cites W2396116692 @default.
- W2007646238 cites W2415856171 @default.
- W2007646238 cites W4242825676 @default.
- W2007646238 cites W4244190411 @default.
- W2007646238 cites W4249025813 @default.
- W2007646238 cites W74909830 @default.
- W2007646238 doi "https://doi.org/10.1155/2012/649290" @default.
- W2007646238 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3168943" @default.
- W2007646238 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22007316" @default.
- W2007646238 hasPublicationYear "2012" @default.
- W2007646238 type Work @default.
- W2007646238 sameAs 2007646238 @default.
- W2007646238 citedByCount "3" @default.
- W2007646238 countsByYear W20076462382012 @default.
- W2007646238 countsByYear W20076462382013 @default.
- W2007646238 countsByYear W20076462382015 @default.
- W2007646238 crossrefType "journal-article" @default.
- W2007646238 hasAuthorship W2007646238A5029930183 @default.
- W2007646238 hasAuthorship W2007646238A5047380294 @default.
- W2007646238 hasAuthorship W2007646238A5066151943 @default.
- W2007646238 hasBestOaLocation W20076462381 @default.
- W2007646238 hasConcept C134018914 @default.
- W2007646238 hasConcept C137627325 @default.
- W2007646238 hasConcept C142724271 @default.
- W2007646238 hasConcept C159047783 @default.
- W2007646238 hasConcept C159654299 @default.
- W2007646238 hasConcept C203014093 @default.
- W2007646238 hasConcept C207886595 @default.
- W2007646238 hasConcept C2779134260 @default.
- W2007646238 hasConcept C2780130043 @default.
- W2007646238 hasConcept C2780366471 @default.
- W2007646238 hasConcept C45189115 @default.
- W2007646238 hasConcept C555293320 @default.
- W2007646238 hasConcept C55851684 @default.
- W2007646238 hasConcept C71924100 @default.
- W2007646238 hasConcept C8891405 @default.
- W2007646238 hasConceptScore W2007646238C134018914 @default.
- W2007646238 hasConceptScore W2007646238C137627325 @default.
- W2007646238 hasConceptScore W2007646238C142724271 @default.
- W2007646238 hasConceptScore W2007646238C159047783 @default.
- W2007646238 hasConceptScore W2007646238C159654299 @default.