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- W2007656554 abstract "Many applications in molecular separation and sensing technology now require devices with uniformity at the nanometer scale over macroscopic areas. Advanced methods for fabrication and manipulation of such artificial tools can greatly increase process speed, selectivity and efficiency. In this work, we present a new synthesis technique for creating ∼mm2 arrays of uniformly tapered nanopores. We investigate the effect of pore size (50-800nm), geometry and surface functionalization on diffusion rates of biomolecules through synthesized membranes. Results are compared against state-of-the-art polycarbonate track etched (PCTE) membranes and other filter technologies. Mass transfer rates are shown to increase up to 15x with tapered geometries compared to cylindrical geometries. Experimental results are supported with molecular calculations.This work was performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344. LLNL-ABS-407641." @default.
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- W2007656554 date "2009-02-01" @default.
- W2007656554 modified "2023-10-17" @default.
- W2007656554 title "Controlled Molecular Transport through Nanofilters with Tapered and Cylindrical Pores" @default.
- W2007656554 doi "https://doi.org/10.1016/j.bpj.2008.12.3852" @default.
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