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- W2007676525 abstract "Mice were exposed to constant internal levels of tritiated water starting at conception and continuing throughout their lives. Chromatin was isolated from seven different tissues (testis, spleen, kidney, thymus, ovary, liver, and bone marrow) taken from these mice. It was fractionated into four components: histone, RNA, DNA, and residual protein. The tritium content of each of these components from each tissue was measured. The tritium content of hemoglobin and liver glycogen isolated from these mice was also measured. The results of these measurements are listed as the specific activity of carbon-bound hydrogens in DNA, hemoglobin, and glycogen relative to the specific activity of tissue water. Also listed are the number of tritium atoms per nucleus in each chromosome component. The results are discussed in terms of the tritium levels expected if humans were exposed to tritiated water. On the basis of known species differences in metabolic processes responsible for incorporating tritium into chromatin it is concluded that humans would incorporate less tritium than similarly exposed mice." @default.
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- W2007676525 date "1977-11-01" @default.
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- W2007676525 title "The Distribution of Tritium in the Glycogen, Hemoglobin, and Chromatin of Mice Receiving Tritium in Their Drinking Water" @default.
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- W2007676525 doi "https://doi.org/10.2307/3574703" @default.
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