Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007681785> ?p ?o ?g. }
- W2007681785 endingPage "834" @default.
- W2007681785 startingPage "823" @default.
- W2007681785 abstract "Background: Heart failure afflicts > 5 million patients in the US, with about 550,000 new diagnoses a year. Side effects and increased mortality limit heart failure treatment. Nesiritide is the newest addition to therapeutic options for treatment of acute decompensated heart failure (ADHF). It has been used as single in-patient infusions, multiple out-patient infusions, and perioperatively to improve hemodynamics and promote diuresis. Initially well-received, meta-analyses suggesting increased mortality and renal dysfunction after nesiritide use were published 4 – 5 years after its introduction in the US. These reports prompted new recommendations on nesiritide use by an expert panel. Objective: Critical review of the studies leading to approval of nesiritide and the current recommendations for its use. Methods: Medline search and Pubmed search using nesiritide or natrecor for text word searches. Conclusion: Nesiritide represents the first drug in a new class designed for treatment of ADHF. In patients with ADHF, nesiritide improves hemodynamic parameters and reduces dyspnea. Questions remain about possible increased mortality and side effects. A continuing study expected to enroll 7000 patients by 2010 has been designed to clarify whether nesiritide reduces mortality, hospital length-of-stay and renal parameters in patients with ADHF." @default.
- W2007681785 created "2016-06-24" @default.
- W2007681785 creator A5070499541 @default.
- W2007681785 creator A5077800087 @default.
- W2007681785 date "2009-06-19" @default.
- W2007681785 modified "2023-10-07" @default.
- W2007681785 title "The role of nesiritide in heart failure" @default.
- W2007681785 cites W1418193820 @default.
- W2007681785 cites W1975728622 @default.
- W2007681785 cites W1975971363 @default.
- W2007681785 cites W1984874696 @default.
- W2007681785 cites W1986558866 @default.
- W2007681785 cites W1988232724 @default.
- W2007681785 cites W1993823264 @default.
- W2007681785 cites W1998213207 @default.
- W2007681785 cites W2004505085 @default.
- W2007681785 cites W2013009184 @default.
- W2007681785 cites W2013128164 @default.
- W2007681785 cites W2018573712 @default.
- W2007681785 cites W2023869949 @default.
- W2007681785 cites W2028618147 @default.
- W2007681785 cites W2029023921 @default.
- W2007681785 cites W2029374006 @default.
- W2007681785 cites W2034178790 @default.
- W2007681785 cites W2034907954 @default.
- W2007681785 cites W2035681674 @default.
- W2007681785 cites W2038454936 @default.
- W2007681785 cites W2049544182 @default.
- W2007681785 cites W2051836732 @default.
- W2007681785 cites W2058542276 @default.
- W2007681785 cites W2060125194 @default.
- W2007681785 cites W2072892297 @default.
- W2007681785 cites W2093245280 @default.
- W2007681785 cites W2118337045 @default.
- W2007681785 cites W2120374545 @default.
- W2007681785 cites W2120722321 @default.
- W2007681785 cites W2123313780 @default.
- W2007681785 cites W2126682768 @default.
- W2007681785 cites W2126706345 @default.
- W2007681785 cites W2126829361 @default.
- W2007681785 cites W2132347735 @default.
- W2007681785 cites W2136483429 @default.
- W2007681785 cites W2138591130 @default.
- W2007681785 cites W2139705590 @default.
- W2007681785 cites W2140292987 @default.
- W2007681785 cites W2141250641 @default.
- W2007681785 cites W2141891466 @default.
- W2007681785 cites W2144397934 @default.
- W2007681785 cites W2157975128 @default.
- W2007681785 cites W2163978931 @default.
- W2007681785 cites W2166719143 @default.
- W2007681785 cites W2168810764 @default.
- W2007681785 cites W2268016673 @default.
- W2007681785 cites W2319534362 @default.
- W2007681785 cites W2328167306 @default.
- W2007681785 cites W2334371071 @default.
- W2007681785 cites W25744554 @default.
- W2007681785 cites W4362070830 @default.
- W2007681785 doi "https://doi.org/10.1517/17425250903042300" @default.
- W2007681785 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19538002" @default.
- W2007681785 hasPublicationYear "2009" @default.
- W2007681785 type Work @default.
- W2007681785 sameAs 2007681785 @default.
- W2007681785 citedByCount "2" @default.
- W2007681785 countsByYear W20076817852020 @default.
- W2007681785 crossrefType "journal-article" @default.
- W2007681785 hasAuthorship W2007681785A5070499541 @default.
- W2007681785 hasAuthorship W2007681785A5077800087 @default.
- W2007681785 hasConcept C126322002 @default.
- W2007681785 hasConcept C164705383 @default.
- W2007681785 hasConcept C177713679 @default.
- W2007681785 hasConcept C2775915353 @default.
- W2007681785 hasConcept C2777386981 @default.
- W2007681785 hasConcept C2778198053 @default.
- W2007681785 hasConcept C2779295919 @default.
- W2007681785 hasConcept C71924100 @default.
- W2007681785 hasConceptScore W2007681785C126322002 @default.
- W2007681785 hasConceptScore W2007681785C164705383 @default.
- W2007681785 hasConceptScore W2007681785C177713679 @default.
- W2007681785 hasConceptScore W2007681785C2775915353 @default.
- W2007681785 hasConceptScore W2007681785C2777386981 @default.
- W2007681785 hasConceptScore W2007681785C2778198053 @default.
- W2007681785 hasConceptScore W2007681785C2779295919 @default.
- W2007681785 hasConceptScore W2007681785C71924100 @default.
- W2007681785 hasIssue "7" @default.
- W2007681785 hasLocation W20076817851 @default.
- W2007681785 hasLocation W20076817852 @default.
- W2007681785 hasOpenAccess W2007681785 @default.
- W2007681785 hasPrimaryLocation W20076817851 @default.
- W2007681785 hasRelatedWork W1504346760 @default.
- W2007681785 hasRelatedWork W1508665971 @default.
- W2007681785 hasRelatedWork W2000589255 @default.
- W2007681785 hasRelatedWork W2042834694 @default.
- W2007681785 hasRelatedWork W2056745954 @default.
- W2007681785 hasRelatedWork W2125804349 @default.
- W2007681785 hasRelatedWork W2143472362 @default.
- W2007681785 hasRelatedWork W2149507015 @default.
- W2007681785 hasRelatedWork W99325504 @default.