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• W2007691102 abstract "mRNA capping is a cotranscriptional event mediated by the association of capping enzyme with the phosphorylated carboxy-terminal domain (CTD) of RNA polymerase II. In the yeast Saccharomyces cerevisiae, capping enzyme is composed of two subunits, the mRNA 5'-triphosphatase (Cet1) and the mRNA guanylyltransferase (Ceg1). Here we map interactions between Ceg1, Cet1, and the CTD. Although the guanylyltransferase subunit can bind alone to the CTD, it cannot be guanylylated unless the triphosphatase subunit is also present. Therefore, the yeast mRNA guanylyltransferase is regulated by allosteric interactions with both the triphosphatase and CTD." @default.
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• W2007691102 date "1998-11-15" @default.
• W2007691102 modified "2023-10-16" @default.
• W2007691102 title "Allosteric interactions between capping enzyme subunits and the RNA polymerase II carboxy-terminal domain" @default.
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• W2007691102 doi "https://doi.org/10.1101/gad.12.22.3482" @default.
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