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- W2007692494 abstract "The predictive value of the dexamethasone suppression test (DST) was evaluated in two consecutive clinical trials involving 99 individuals treated with amitriptyline or desipramine. Following one week observation, and following one week on lowdose desipramine or amitriptyline (50 mg), all patients who remained depressed (Hamilton score 16 or greater) were given a full clinical trial of either desipramine or amitriptyline (150–300mg/day) over a minimum 3–5 week period. In all, 68 patients required this trial, 31 receiving amitriptyline and 37 receiving desipramine. For these patients there was no relationship between DST suppression/non-suppression vs clinical response to either desipramine or amitriptyline. There was a non-significant trend for suppressors (negative DST) to respond either spontaneously or to low-dose desipramine or amitriptyline as opposed to non-suppressors (positive DST)." @default.
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- W2007692494 date "1986-01-01" @default.
- W2007692494 modified "2023-09-27" @default.
- W2007692494 title "The Dexamethasone Suppression Test (DST) in Predicting Response to Desipramine and Amitriptyline in Depressed Outpatients" @default.
- W2007692494 doi "https://doi.org/10.1097/00004850-198601000-00003" @default.
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