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- W2007698745 abstract "Letters and Corrections1 September 1980Aspirin-Induced Hepatic Encephalopathy and Chronic Liver DiseaseANDREW I. LAZAROVITS, B.SC., M.D., GEOFFREY M. ROBINSON, M.B., CH.B., PAUL DEVENYI, M.D.ANDREW I. LAZAROVITS, B.SC., M.D.Search for more papers by this author, GEOFFREY M. ROBINSON, M.B., CH.B.Search for more papers by this author, PAUL DEVENYI, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-93-3-510_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Hepatocellular toxicity secondary to aspirin has been reported (1-4), but to our knowledge the drug has not been implicated as a precipitant of hepatic encephalopathy in adults. We report the case of a patient with chronic alcoholic liver disease who developed hepatic encephalopathy secondary to aspirin toxcity, which was reproduced by a rechallenge experiment.A 56-year-old chronic alcoholic woman with biopsy-proven micronodular cirrhosis was admitted with hepatic encephalopathy. She had been taking approximately 5 g of aspirin per day for severe left hip pain due to progressive osteoarthritis. She had not been drinking ethanol for a month...References1. SEAMANISHAKPLOTZ WKP. Aspirin-induced hepatotoxicity in patients with systemic lupus erythematosus. Ann Intern Med. 1974;80:1-8. LinkGoogle Scholar2. WOLFEMETZGERGOLDSTEIN JAR. Aspirin hepatitis. Ann Intern Med. 1974;80:74-6. LinkGoogle Scholar3. MANSOTARANTANYDICK CAI. Effect of aspirin administration on serum glutamic oxaloacetic and glutamic pyruvic transaminases in children. Proc Soc Exp Biol Med. 1956;93:84-8. CrossrefMedlineGoogle Scholar4. RICHJOHNSON PJ. Salicylate hepatotoxicity in patients with juvenile rheumatoid arthritis. Arthritis Rheum. 1973;16:1-9. CrossrefMedlineGoogle Scholar5. PRESCOTT L. Antipyretic analgesics. In: DUKES MNG., ed.: Side Effects of Drugs Annual 1. Amsterdam: Exerpta Medica; 1977:66. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Addiction Research Foundation University of Toronto Toronto, Ontario Canada PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySevere hepatoxicity caused by aspirin overdose: a case report 1 September 1980Volume 93, Issue 3Page: 510-510KeywordsAlcoholicsAspirinBrain diseasesChronic liver diseaseCirrhosisEthanolHipLiver diseasesOsteoarthritisToxicity Issue Published: 1 September 1980 PDF downloadLoading ..." @default.
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- W2007698745 title "Aspirin-Induced Hepatic Encephalopathy and Chronic Liver Disease" @default.
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