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- W2007706680 abstract "For decades, scientists have described numerous protein pathways and functions. Much of a protein's function depends on its interactions with different partners, and those partners can change depending on the cell type or system. The P2X7 receptor (P2X7R) is one such multifunctional protein that is related to multiple partners and signaling pathways. The relationship between P2X7R and different enzymes involved in lipid metabolism represents a relatively new field in P2X7R research. This field of research began in epithelial cells and currently includes immune and nervous cells. The P2X7R-lipid metabolism pathway is related to many biological functions of P2X7R, such as cell death and pathogen clearance, and this signaling pathway may be involved in many functions that are dependent on bioactive lipids. In the present review, we will attempt to summarize data related to the P2X7R-lipid metabolism pathway, focusing on signaling pathways and their biological relevance to the immune system and infection." @default.
- W2007706680 created "2016-06-24" @default.
- W2007706680 creator A5020027555 @default.
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- W2007706680 creator A5051817032 @default.
- W2007706680 creator A5063963821 @default.
- W2007706680 creator A5090070638 @default.
- W2007706680 date "2011-08-16" @default.
- W2007706680 modified "2023-09-24" @default.
- W2007706680 title "Lipid metabolism modulation by the P2X7 receptor in the immune system and during the course of infection: new insights into the old view" @default.
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