Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007745812> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2007745812 endingPage "1050" @default.
- W2007745812 startingPage "1041" @default.
- W2007745812 abstract "Aldehydes are toxic environmental contaminants which cause severe health hazards. There is a growing need by industries and regulatory agencies for the development of tools able to assess the potential hazardous effects of chemicals on living organisms. In this background, multivariate image analysis combined with quantitative structure–toxicity relationships (MIA-QSTR) was used to evaluate the toxicity of aromatic aldehydes to Tetrahymena pyriformis. The techniques of genetic algorithm–partial least squares (GA-PLS) were applied effectively as MIA descriptor selection and mapping tools. In MIA-QSTR evaluation, pixels of 2D images of chemical structures could be used to recognize physicochemical information and predict changes in the toxicities. The resulting MIA-QSTR explains 90.3% leave-one-out predicted variance and 93.1% external predicted variance. The MIA-QSTR/GA-PLS performances were validated using various evaluation techniques such as cross-validation, applicability domain and Y-scrambling procedures, suggesting that the present methodology together with mechanistic interpretation may be useful to evaluate toxicity, safety and risk assessment of toxic environmental contaminants." @default.
- W2007745812 created "2016-06-24" @default.
- W2007745812 creator A5035187631 @default.
- W2007745812 date "2013-12-01" @default.
- W2007745812 modified "2023-09-27" @default.
- W2007745812 title "Straightforward MIA‐QSTR evaluation of environmental toxicities of aromatic aldehydes toTetrahymena pyriformis" @default.
- W2007745812 cites W1590280487 @default.
- W2007745812 cites W1986063539 @default.
- W2007745812 cites W1998549010 @default.
- W2007745812 cites W1999175098 @default.
- W2007745812 cites W2015425076 @default.
- W2007745812 cites W2015931265 @default.
- W2007745812 cites W2040715087 @default.
- W2007745812 cites W2042516100 @default.
- W2007745812 cites W2044893023 @default.
- W2007745812 cites W2061139820 @default.
- W2007745812 cites W2076879979 @default.
- W2007745812 cites W2081198257 @default.
- W2007745812 cites W2094431892 @default.
- W2007745812 cites W2153805743 @default.
- W2007745812 doi "https://doi.org/10.1080/1062936x.2013.840678" @default.
- W2007745812 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24313440" @default.
- W2007745812 hasPublicationYear "2013" @default.
- W2007745812 type Work @default.
- W2007745812 sameAs 2007745812 @default.
- W2007745812 citedByCount "1" @default.
- W2007745812 countsByYear W20077458122022 @default.
- W2007745812 crossrefType "journal-article" @default.
- W2007745812 hasAuthorship W2007745812A5035187631 @default.
- W2007745812 hasConcept C105795698 @default.
- W2007745812 hasConcept C107872376 @default.
- W2007745812 hasConcept C11413529 @default.
- W2007745812 hasConcept C164126121 @default.
- W2007745812 hasConcept C178790620 @default.
- W2007745812 hasConcept C182548165 @default.
- W2007745812 hasConcept C185592680 @default.
- W2007745812 hasConcept C186060115 @default.
- W2007745812 hasConcept C22354355 @default.
- W2007745812 hasConcept C2777166614 @default.
- W2007745812 hasConcept C29730261 @default.
- W2007745812 hasConcept C2991723024 @default.
- W2007745812 hasConcept C33923547 @default.
- W2007745812 hasConcept C55493867 @default.
- W2007745812 hasConcept C71240020 @default.
- W2007745812 hasConcept C86803240 @default.
- W2007745812 hasConceptScore W2007745812C105795698 @default.
- W2007745812 hasConceptScore W2007745812C107872376 @default.
- W2007745812 hasConceptScore W2007745812C11413529 @default.
- W2007745812 hasConceptScore W2007745812C164126121 @default.
- W2007745812 hasConceptScore W2007745812C178790620 @default.
- W2007745812 hasConceptScore W2007745812C182548165 @default.
- W2007745812 hasConceptScore W2007745812C185592680 @default.
- W2007745812 hasConceptScore W2007745812C186060115 @default.
- W2007745812 hasConceptScore W2007745812C22354355 @default.
- W2007745812 hasConceptScore W2007745812C2777166614 @default.
- W2007745812 hasConceptScore W2007745812C29730261 @default.
- W2007745812 hasConceptScore W2007745812C2991723024 @default.
- W2007745812 hasConceptScore W2007745812C33923547 @default.
- W2007745812 hasConceptScore W2007745812C55493867 @default.
- W2007745812 hasConceptScore W2007745812C71240020 @default.
- W2007745812 hasConceptScore W2007745812C86803240 @default.
- W2007745812 hasIssue "12" @default.
- W2007745812 hasLocation W20077458121 @default.
- W2007745812 hasLocation W20077458122 @default.
- W2007745812 hasOpenAccess W2007745812 @default.
- W2007745812 hasPrimaryLocation W20077458121 @default.
- W2007745812 hasRelatedWork W1978362138 @default.
- W2007745812 hasRelatedWork W1983018026 @default.
- W2007745812 hasRelatedWork W2007864533 @default.
- W2007745812 hasRelatedWork W2035203910 @default.
- W2007745812 hasRelatedWork W2044235819 @default.
- W2007745812 hasRelatedWork W2076147571 @default.
- W2007745812 hasRelatedWork W2115606156 @default.
- W2007745812 hasRelatedWork W2142654007 @default.
- W2007745812 hasRelatedWork W2272651590 @default.
- W2007745812 hasRelatedWork W3163861970 @default.
- W2007745812 hasVolume "24" @default.
- W2007745812 isParatext "false" @default.
- W2007745812 isRetracted "false" @default.
- W2007745812 magId "2007745812" @default.
- W2007745812 workType "article" @default.