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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007751632> ?p ?o ?g. }

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• W2007751632 abstract "The prevalence of genetically engineered mice in medical research has led to ever increasing storage costs. Trehalose has a significant beneficial effect in preserving the developmental potential of mouse sperm following partial desiccation and storage at temperatures above freezing. Using multi-isotope imaging mass spectrometry, we are able to image and measure trehalose in individual spermatozoa. We provide the first evidence that trehalose penetrates the nucleus of a mammalian cell, permitting tolerance to desiccation. These results have broad implications for long-term storage of mammalian cells." @default.
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• W2007751632 date "2012-08-27" @default.
• W2007751632 modified "2023-10-14" @default.
• W2007751632 title "3D Multi-isotope Imaging Mass Spectrometry Reveals Penetration of 18O-Trehalose in Mouse Sperm Nucleus" @default.
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• W2007751632 doi "https://doi.org/10.1371/journal.pone.0042267" @default.
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