FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007754059> ?p ?o ?g. }

• W2007754059 endingPage "7363" @default.
• W2007754059 startingPage "7356" @default.
• W2007754059 abstract "The accumulation of acetylcholine receptors (AChRs) at nerve terminals is critical for signal transmission at the neuromuscular junction, and rapsyn is essential for this process. Previous studies suggest that AChRs might direct rapsyn self-clusters to the synapse. In vivo experiments with fluorescently tagged AChR or rapsyn in zebrafish larvae revealed that rapsyn self-clusters separate from AChRs did not exist before synapse formation. Examination of rapsyn in the AChR-less mutant sofa potato revealed that rapsyn in the absence of AChR was localized in the Golgi complex. Expression of muscle-type AChR in sofa potato restored synaptic clustering of rapsyn, while neuronal type AChR had no effect. To determine whether this requirement of protein interaction is reciprocal, we examined the mutant twitch once, which has a missense mutation in rapsyn. While the AChRs distributed nonsynaptically on the plasma membrane in twitch once , mutant rapsyn was retained in the Golgi complex. We conclude that AChRs enable the transport of rapsyn from the Golgi complex to the plasma membrane through a molecule-specific interaction." @default.
• W2007754059 created "2016-06-24" @default.
• W2007754059 creator A5011987568 @default.
• W2007754059 creator A5043600557 @default.
• W2007754059 creator A5062296371 @default.
• W2007754059 creator A5079322428 @default.
• W2007754059 date "2012-05-23" @default.
• W2007754059 modified "2023-10-03" @default.
• W2007754059 title "Acetylcholine Receptors Enable the Transport of Rapsyn from the Golgi Complex to the Plasma Membrane" @default.
• W2007754059 cites W1508830093 @default.
• W2007754059 cites W1512382989 @default.
• W2007754059 cites W1524537326 @default.
• W2007754059 cites W1541331419 @default.
• W2007754059 cites W1581492997 @default.
• W2007754059 cites W1598713761 @default.
• W2007754059 cites W1669653395 @default.
• W2007754059 cites W1900806927 @default.
• W2007754059 cites W1943218535 @default.
• W2007754059 cites W1947859348 @default.
• W2007754059 cites W1963527409 @default.
• W2007754059 cites W1963556093 @default.
• W2007754059 cites W1979158821 @default.
• W2007754059 cites W1980047938 @default.
• W2007754059 cites W1981325854 @default.
• W2007754059 cites W1984522719 @default.
• W2007754059 cites W1990600579 @default.
• W2007754059 cites W1992755274 @default.
• W2007754059 cites W1996683805 @default.
• W2007754059 cites W2007179634 @default.
• W2007754059 cites W2013792051 @default.
• W2007754059 cites W2017757562 @default.
• W2007754059 cites W2022605837 @default.
• W2007754059 cites W2027457598 @default.
• W2007754059 cites W2028453857 @default.
• W2007754059 cites W2044163971 @default.
• W2007754059 cites W2047379519 @default.
• W2007754059 cites W2052992979 @default.
• W2007754059 cites W2063791205 @default.
• W2007754059 cites W2065934844 @default.
• W2007754059 cites W2066037819 @default.
• W2007754059 cites W2068031262 @default.
• W2007754059 cites W2068836997 @default.
• W2007754059 cites W2081415771 @default.
• W2007754059 cites W2094697595 @default.
• W2007754059 cites W2103035579 @default.
• W2007754059 cites W2103944414 @default.
• W2007754059 cites W2106744303 @default.
• W2007754059 cites W2112783241 @default.
• W2007754059 cites W2115710616 @default.
• W2007754059 cites W2128686747 @default.
• W2007754059 cites W2131879548 @default.
• W2007754059 cites W2136470556 @default.
• W2007754059 cites W2148646540 @default.
• W2007754059 cites W2155203079 @default.
• W2007754059 cites W2164592902 @default.
• W2007754059 cites W2170194206 @default.
• W2007754059 cites W2170304743 @default.
• W2007754059 cites W2171955681 @default.
• W2007754059 cites W4240915676 @default.
• W2007754059 doi "https://doi.org/10.1523/jneurosci.0397-12.2012" @default.
• W2007754059 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3366470" @default.
• W2007754059 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22623681" @default.
• W2007754059 hasPublicationYear "2012" @default.
• W2007754059 type Work @default.
• W2007754059 sameAs 2007754059 @default.
• W2007754059 citedByCount "16" @default.
• W2007754059 countsByYear W20077540592014 @default.
• W2007754059 countsByYear W20077540592015 @default.
• W2007754059 countsByYear W20077540592016 @default.
• W2007754059 countsByYear W20077540592017 @default.
• W2007754059 countsByYear W20077540592018 @default.
• W2007754059 countsByYear W20077540592019 @default.
• W2007754059 countsByYear W20077540592020 @default.
• W2007754059 countsByYear W20077540592021 @default.
• W2007754059 countsByYear W20077540592022 @default.
• W2007754059 crossrefType "journal-article" @default.
• W2007754059 hasAuthorship W2007754059A5011987568 @default.
• W2007754059 hasAuthorship W2007754059A5043600557 @default.
• W2007754059 hasAuthorship W2007754059A5062296371 @default.
• W2007754059 hasAuthorship W2007754059A5079322428 @default.
• W2007754059 hasBestOaLocation W20077540591 @default.
• W2007754059 hasConcept C119062480 @default.
• W2007754059 hasConcept C127445978 @default.
• W2007754059 hasConcept C158617107 @default.
• W2007754059 hasConcept C169760540 @default.
• W2007754059 hasConcept C170493617 @default.
• W2007754059 hasConcept C185592680 @default.
• W2007754059 hasConcept C200170125 @default.
• W2007754059 hasConcept C2777240379 @default.
• W2007754059 hasConcept C55493867 @default.
• W2007754059 hasConcept C80161118 @default.
• W2007754059 hasConcept C86803240 @default.
• W2007754059 hasConcept C95444343 @default.
• W2007754059 hasConceptScore W2007754059C119062480 @default.
• W2007754059 hasConceptScore W2007754059C127445978 @default.
• W2007754059 hasConceptScore W2007754059C158617107 @default.
• W2007754059 hasConceptScore W2007754059C169760540 @default.
• W2007754059 hasConceptScore W2007754059C170493617 @default.

• next