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- W2007755775 abstract "The standard classification scheme of the genetic code is organized for alphabetic ordering of nucleotides. Here we introduce the new, ideal classification scheme in compact form, for the first time generated by codon sextets encoding Ser, Arg and Leu amino acids. The new scheme creates the known purine/pyrimidine, codon-anticodon, and amino/keto type symmetries and a novel A+U rich/C+G rich symmetry. This scheme is built from leading and nonleading groups of 32 codons each. In the ensuing 4 × 16 scheme, based on trinucleotide quadruplets, Ser has a central role as initial generator. Six codons encoding Ser and six encoding Arg extend continuously along a linear array in the leading group, and together with four of six Leu codons uniquely define construction of the leading group. The remaining two Leu codons enable construction of the nonleading group. The ideal genetic code suggests the evolution of genetic code with serine as an initiator." @default.
- W2007755775 created "2016-06-24" @default.
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- W2007755775 date "2014-06-01" @default.
- W2007755775 modified "2023-09-27" @default.
- W2007755775 title "Codon sextets with leading role of serine create “ideal” symmetry classification scheme of the genetic code" @default.
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- W2007755775 doi "https://doi.org/10.1016/j.gene.2014.04.009" @default.
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