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• W2007758955 abstract "The present study evaluated the neuroprotective potential of prostaglandin A1 (PGA1) in rodent models of focal cerebral ischemia. PGA1 33 nmol reduced infarction volume by about 43% (P < 0.05) when administered intracerebroventricularly before and after transient ischemia in mice. PGA1 16.5-66 nmol diminished infarction volume by 18% to 27% (P < 0.01) when administered immediately following permanent ischemia in rats. PGA1 treatment also significantly ameliorated motor dysfunction after brain ischemia. These results suggest that PGA1 protects neurons from ischemic injury." @default.
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• W2007758955 date "2005-03-01" @default.
• W2007758955 modified "2023-09-27" @default.
• W2007758955 title "Neuroprotective effects of prostaglandin A1 in animal models of focal ischemia" @default.
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• W2007758955 doi "https://doi.org/10.1016/j.brainres.2005.01.046" @default.
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