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- W2007800550 abstract "Twelve new diterpenoids, isoadenolins A–L (1–12), and 24 known ones were isolated from the aerial parts of Isodon adenolomus. Their structures were identified using spectroscopic data, and the absolute configurations of 1 and 14 were determined by single-crystal X-ray diffraction. Selected compounds were evaluated for their in vitro cytotoxicity against human tumor HL-60, SMMC-7721, A-549, MCF-7, and SW-480 cell lines. Compounds 9, 13–16, and 21 showed significant inhibitory effects on all five cells, with IC50 values in the range 0.7–9.7 μM." @default.
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- W2007800550 date "2011-05-02" @default.
- W2007800550 modified "2023-10-16" @default.
- W2007800550 title "Structure and Cytotoxicity of Diterpenoids from <i>Isodon adenolomus</i>" @default.
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- W2007800550 doi "https://doi.org/10.1021/np200140j" @default.
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