Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007802313> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W2007802313 endingPage "8" @default.
- W2007802313 startingPage "1" @default.
- W2007802313 abstract "Several imidazo[4,5-d]pyridazine nucleosides which are structurally similar to inosine were synthesized. Anhydrous stannic chloride-catalyzed condensation of persilylated imidazo[4,5-d]-pyridazin-4(5H)one (1) and imidazo[4,5-d]pyridazine-4,7(5H,6H)dione (16) with 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose (3) provided (after sodium methoxide deblocking) 6-β-D-ribo furanosylimidazo[4,5-d]pyridazin-4(5H)one (5) and 3,6-di-(β-D-ribofuranosyI)imidazo[4,5-d]pyridazin-4-one (7); and 1-(β-D-ribofuranosyl)imidazo[4,5-d]pyridazine-4,7(5H,6H)dione (19) and 1,5 or 6-di-(β-D-ribofuranosyl)imidazo[4,5-d ]pyridazine-4,7(5H or 6H)dione (21), respeeitvely. 4,7-Diehloro-1-β-D-ribofuranosylimidazo[4,5-d]pyridazine (12) and dimethyl 1-β-D-ribofuranosylimidazole-4,5-dicarboxylate (26), both prepared from stannic chloride-catalyzed ribosylations of the corresponding heterocycles, were converted in several steps to 3-β-D-ribo-furanosy limidazo[4,5-d]pyridazin-4(5H)one (14) and nucleosidc 19, respectively. Acid-catalyzed isopropylidenation of mesomeric betaine 7 or nuclcoside 14 provided 3-(2,3-isopropylidene-β-D-ribofuranosyl)imidazo[4,5-d]pyrizin-4(5H)one (31). 1-β-D-Ribofuranosylimidazo[4,5-d]-pyridazine (29) was obtained in several steps from nueleoside 12. The structure of the nucleosides was established by the use of carbon-13 and proton nmr." @default.
- W2007802313 created "2016-06-24" @default.
- W2007802313 creator A5030018903 @default.
- W2007802313 creator A5063472750 @default.
- W2007802313 creator A5075105311 @default.
- W2007802313 date "1978-01-01" @default.
- W2007802313 modified "2023-10-09" @default.
- W2007802313 title "Synthesis of imidazo[4,5-d]pyridazine nucleosides related to inosine" @default.
- W2007802313 cites W1982301628 @default.
- W2007802313 cites W1984386728 @default.
- W2007802313 cites W1991597416 @default.
- W2007802313 cites W1997360594 @default.
- W2007802313 cites W1999158421 @default.
- W2007802313 cites W2026730597 @default.
- W2007802313 cites W2027988227 @default.
- W2007802313 cites W2039656086 @default.
- W2007802313 cites W2068911163 @default.
- W2007802313 cites W2085530150 @default.
- W2007802313 cites W2323008654 @default.
- W2007802313 cites W2332897344 @default.
- W2007802313 cites W2335651060 @default.
- W2007802313 cites W2399800726 @default.
- W2007802313 cites W2482764499 @default.
- W2007802313 cites W2041170258 @default.
- W2007802313 doi "https://doi.org/10.1002/jhet.5570150101" @default.
- W2007802313 hasPublicationYear "1978" @default.
- W2007802313 type Work @default.
- W2007802313 sameAs 2007802313 @default.
- W2007802313 citedByCount "14" @default.
- W2007802313 crossrefType "journal-article" @default.
- W2007802313 hasAuthorship W2007802313A5030018903 @default.
- W2007802313 hasAuthorship W2007802313A5063472750 @default.
- W2007802313 hasAuthorship W2007802313A5075105311 @default.
- W2007802313 hasConcept C178790620 @default.
- W2007802313 hasConcept C181199279 @default.
- W2007802313 hasConcept C185592680 @default.
- W2007802313 hasConcept C21951064 @default.
- W2007802313 hasConcept C24961977 @default.
- W2007802313 hasConcept C2777355660 @default.
- W2007802313 hasConcept C2777610669 @default.
- W2007802313 hasConcept C71240020 @default.
- W2007802313 hasConceptScore W2007802313C178790620 @default.
- W2007802313 hasConceptScore W2007802313C181199279 @default.
- W2007802313 hasConceptScore W2007802313C185592680 @default.
- W2007802313 hasConceptScore W2007802313C21951064 @default.
- W2007802313 hasConceptScore W2007802313C24961977 @default.
- W2007802313 hasConceptScore W2007802313C2777355660 @default.
- W2007802313 hasConceptScore W2007802313C2777610669 @default.
- W2007802313 hasConceptScore W2007802313C71240020 @default.
- W2007802313 hasIssue "1" @default.
- W2007802313 hasLocation W20078023131 @default.
- W2007802313 hasOpenAccess W2007802313 @default.
- W2007802313 hasPrimaryLocation W20078023131 @default.
- W2007802313 hasRelatedWork W1973021261 @default.
- W2007802313 hasRelatedWork W1993711503 @default.
- W2007802313 hasRelatedWork W2075962927 @default.
- W2007802313 hasRelatedWork W2076591187 @default.
- W2007802313 hasRelatedWork W2085530150 @default.
- W2007802313 hasRelatedWork W2089998154 @default.
- W2007802313 hasRelatedWork W2093424242 @default.
- W2007802313 hasRelatedWork W2172738659 @default.
- W2007802313 hasRelatedWork W2394731951 @default.
- W2007802313 hasRelatedWork W3217767676 @default.
- W2007802313 hasVolume "15" @default.
- W2007802313 isParatext "false" @default.
- W2007802313 isRetracted "false" @default.
- W2007802313 magId "2007802313" @default.
- W2007802313 workType "article" @default.