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- W2007803469 abstract "A 12-year-old girl with lifelong hemorrhagic episodes was found to have both a dys-form of homozygous factor XI deficiency and heterozygous factor XII deficiency. The heredity of the coagulation defects was confirmed by family studies. Severe bleeding after dental surgery occurred in spite of replacement therapy and local measures including fibrin glue. Our findings suggest that the risk of bleeding in patients with homozygous factor XI deficiency must not be underestimated and that the most effective measure is the transfusion of sufficient amounts of fresh frozen plasma until at least the 5th postoperative day." @default.
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- W2007803469 date "1985-01-01" @default.
- W2007803469 modified "2023-10-01" @default.
- W2007803469 title "Combined Dys-Form of Homozygous Factor XI Deficiency and Heterozygous Factor XII Deficiency" @default.
- W2007803469 doi "https://doi.org/10.1159/000215147" @default.
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